Bioactive compounds and biomedical applications of endophytic fungi: a recent review

AH Hashem, MS Attia, EK Kandil, MM Fawzi… - Microbial Cell …, 2023 - Springer
Human life has been significantly impacted by the creation and spread of novel species of
antibiotic-resistant bacteria and virus strains that are difficult to manage. Scientists and …

Endophytic fungi: Key insights, emerging prospects, and challenges in natural product drug discovery

P Tiwari, H Bae - Microorganisms, 2022 - mdpi.com
Plant-associated endophytes define an important symbiotic association in nature and are
established bio-reservoirs of plant-derived natural products. Endophytes colonize the …

Endophytic Penicillium species and their agricultural, biotechnological, and pharmaceutical applications

RMK Toghueo, FF Boyom - 3 Biotech, 2020 - Springer
Penicillium genus constituted by over 200 species is one of the largest and fascinating
groups of fungi, particularly well established as a source of antibiotics. Endophytic …

Endophytic fungi: a source of potential antifungal compounds

SK Deshmukh, MK Gupta, V Prakash, S Saxena - Journal of Fungi, 2018 - mdpi.com
The emerging and reemerging forms of fungal infections encountered in the course of
allogeneic bone marrow transplantations, cancer therapy, and organ transplants have …

Polysulfurating reagent design for unsymmetrical polysulfide construction

X Xiao, J Xue, X Jiang - Nature communications, 2018 - nature.com
From life science to material science, to pharmaceutical industry, and to food chemistry,
polysulfides are vital structural scaffolds. However, there are limited synthetic methods for …

Omnipolyphilins A and B: Chlorinated Cyclotetrapeptides and Naphtho-α-pyranones from the Plant Nematode-Derived Fungus Polyphilus sieberi

JP Wennrich, SS Ebada, E Sepanian… - Journal of Agricultural …, 2024 - ACS Publications
Chemical exploration for two isolates of the recently described ascomycete species
Polyphilus sieberi, derived from the eggs of the plant parasitic nematode Heterodera filipjevi …

Structurally uncommon secondary metabolites derived from endophytic fungi

HE Ortega, D Torres-Mendoza, Z Caballero E… - Journal of Fungi, 2021 - mdpi.com
Among microorganisms, endophytic fungi are the least studied, but they have attracted
attention due to their high biological diversity and ability to produce novel and bioactive …

Dithiodiketopiperazine derivatives from endophytic fungi Trichoderma harzianum and Epicoccum nigrum

H Harwoko, G Daletos, F Stuhldreier, J Lee… - Natural product …, 2021 - Taylor & Francis
A new epidithiodiketopiperazine (ETP), pretrichodermamide G (1), along with three known
(epi) dithiodiketopiparazines (2-4) were isolated from cultures of Trichoderma harzianum …

Synthesis of Unsymmetrical Trisulfides from S‐Substituted Sulphenylthiosulphates

S Liang, L Ma, Z Guo, F Liu, Z Lin… - Angewandte Chemie …, 2024 - Wiley Online Library
Trisulfide unit is widely found in natural products and has garnered attention due to the
unique pharmacological and physiochemical properties. However, despite limited progress …

Structural diversity and biological activities of the cyclodipeptides from fungi

X Wang, Y Li, X Zhang, D Lai, L Zhou - Molecules, 2017 - mdpi.com
Cyclodipeptides, called 2, 5-diketopiperazines (2, 5-DKPs), are obtained by the
condensation of two amino acids. Fungi have been considered to be a rich source of novel …