Cathelicidins are antimicrobial peptides produced by humans and animals in response to
various pathogenic microbes. This review intends to provide a brief overview of the …

Antimicrobial peptides are predominantly small cationic polypeptides that are classified
together on the basis of these molecules to directly kill or inhibit the growth of …

Control of tuberculosis worldwide depends on our understanding of human immune
mechanisms, which combat the infection. Acquired T cell responses are critical for host …

Tripartite motif-containing proteins (TRIMs) play a variety of recently described roles in
innate immunity. Although many TRIMs regulate type I IFN expression following cytosolic …

Context: Vitamin D has regulatory effects on innate and adaptive immunity. Curiously,
hereditary vitamin D–resistant rickets (HVDRR) patients show no increased incidence of …

Mycobacterium tuberculosis is a successful intracellular pathogen. Numerous host innate
immune responses signaling pathways are induced upon mycobacterium invasion, however …

Tuberculosis is an ancient infectious disease that remains a threat for public health around
the world. Although the etiological agent as well as tuberculosis pathogenesis is well known …

Despite considerable research effort, the molecular mechanisms of Mycobacterium
tuberculosis (Mtb) virulence remain unclear. Cholesterol oxidase (ChoD), an extracellular …

Objectives and design Dendritic cells (DCs) are one of the key immune cells in bridging
innate and adaptive immune response against Mycobacterium tuberculosis (Mtb) infection …

Background Recent studies suggest that the incidence and severity of tuberculosis is
associated with low levels of vitamin D. Even though individuals living in Ethiopia have a …