Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes
mellitus (DM), leading to the greatest morbidity and mortality and resulting in a huge …

Neurodegenerative disorders are accompanied by neuronal degeneration and glial
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …

Key Clinical Points Diabetic Sensory and Motor Neuropathy Symptoms of distal symmetric
motor and sensory polyneuropathy may be “positive”(manifested as sensations of tingling …

Sensory profiles are heterogeneous in neuropathic pain disorders, and subgroups of
patients respond differently to treatment. To further explore this, patients in the COMBO-DN …

Painful diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus,
affecting, by some estimates, up to one quarter of diabetic patients. Since 2010, no fewer …

The worldwide increase in the prevalence of Diabetes mellitus (DM) has highlighted the
need for increased research efforts into treatment options for both the disease itself and its …

OBJECTIVE We aimed to identify doses of mirogabalin (DS-5565) providing clinically
meaningful efficacy with manageable side effects for treatment of diabetic peripheral …

Background Although previous reports have revealed the therapeutic potential of stem cell
transplantation in diabetic polyneuropathy, the effects of cell transplantation on long-term …

Distal symmetric polyneuropathy (DSPN), the most common form of diabetic neuropathy,
has a complex pathophysiology and can be a major source of physical and psychologic …

Paclitaxel, a chemotherapy drug for solid tumors, induces peripheral painful neuropathy.
Bee venom acupuncture (BVA) has been reported to have potent analgesic effects, which …