Small molecules with molecular weights less than 1500 Da represented by natural
metabolites such as amino acids, nucleotides, carbohydrates, lipids, flavonoids, alkaloids …

The outbreak of pandemics (eg, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2 in 2019), influenza A viruses (H1N1 in 2009), etc.), and worldwide spike in the aging …

Oxidation is the main pathway of drug metabolism and cytochrome P-450 (CYP450)
enzymes account for over 80% of drug oxidation. The chemical outcome of this first-pass …

Environmental issues have become a worldwide problem due to the trace-level
contamination of toxic pollutants in aqueous environments, which affects wildlife and human …

Drugs are metabolized within the liver (pH 7.4) by phase I and phase II metabolism. During
the process, reactive metabolites can be formed that react covalently with biomolecules and …

In this study, Raman time-domain spectroscopy (R-TDS) was used to record the spectra of β-
alanine, D-alanine, L-alanine, and DL-alanine molecules in the Raman shift range of 250 …

建立了检测鱼, 虾, 泥鳅和螃蟹等水产品中乙氧基喹啉和乙氧基喹啉二聚体残留的高效液相色谱-
串联质谱(HPLC-MS/MS) 方法. 在样品制备时加入适量维生素C, 以乙腈作为提取溶剂 …

Type B hepatotoxicity has been reported for thiopurines, and this has limited their clinical
uses. Although a lot of research has been done on thiopurines, the precise mechanism of …

An analytical method was developed for the simultaneous determination of ethoxyquinoline
and ethoxyquinoline dimer residues in aquatic products such as fishes, shrimps, loaches …