[PDF][PDF] Metabolic flexibility: hibernation, torpor, and estivation

JF Staples - Compr Physiol, 2016 - uwo.ca
Many environmental conditions can constrain the ability of animals to obtain sufficient food
energy, or transform that food energy into useful chemical forms. To survive extended …

Metabolic suppression in mammalian hibernation: the role of mitochondria

JF Staples - Journal of Experimental Biology, 2014 - journals.biologists.com
Hibernation evolved in some small mammals that live in cold environments, presumably to
conserve energy when food supplies are low. Throughout the winter, hibernators cycle …

The regulation of food intake in mammalian hibernators: a review

GL Florant, JE Healy - Journal of Comparative Physiology B, 2012 - Springer
One of the most profound hallmarks of mammalian hibernation is the dramatic reduction in
food intake during the winter months. Several species of hibernator completely cease food …

Mitochondrial metabolic suppression and reactive oxygen species production in liver and skeletal muscle of hibernating thirteen-lined ground squirrels

JCL Brown, DJ Chung, KR Belgrave… - American Journal of …, 2012 - journals.physiology.org
During hibernation, animals cycle between periods of torpor, during which body temperature
(Tb) and metabolic rate (MR) are suppressed for days, and interbout euthermia (IBE), during …

Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial leak respiration

K Salin, SK Auer, AM Rudolf… - Physiological and …, 2016 - journals.uchicago.edu
Standard metabolic rate (SMR) and maximum metabolic rate (MMR) typically vary two-or
threefold among conspecifics, with both traits assumed to significantly impact fitness …

Mitochondrial metabolism in hibernation: regulation and implications

JF Staples, KE Mathers, BM Duffy - Physiology, 2022 - journals.physiology.org
Hibernators rapidly and reversibly suppress mitochondrial respiration and whole animal
metabolism. Posttranslational modifications likely regulate these mitochondrial changes …

Differential posttranslational modification of mitochondrial enzymes corresponds with metabolic suppression during hibernation

KE Mathers, JF Staples - American Journal of Physiology …, 2019 - journals.physiology.org
During hibernation, small mammals, including the 13-lined ground squirrel (Ictidomys
tridecemlineatus), cycle between two distinct metabolic states: torpor, where metabolic rate …

Proteomics approaches shed new light on hibernation physiology

KR Grabek, SL Martin, AG Hindle - Journal of Comparative Physiology B, 2015 - Springer
The broad phylogenetic distribution and rapid phenotypic transitions of mammalian
hibernators imply that hibernation is accomplished by differential expression of common …

Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes

KE Mathers, SV McFarlane, L Zhao… - Journal of Comparative …, 2017 - Springer
Small hibernators cycle between periods of torpor, with body temperature (T b)
approximately 5° C, and interbout euthermia (IBE), where T b is approximately 37° C. During …

Rapid cortisol signaling in response to acute stress involves changes in plasma membrane order in rainbow trout liver

L Dindia, E Faught, Z Leonenko… - American Journal …, 2013 - journals.physiology.org
The activation of genomic signaling in response to stressor-mediated cortisol elevation has
been studied extensively in teleosts. However, very little is known about the rapid signaling …