Photodynamic and antibiotic therapy in combination against bacterial infections: efficacy, determinants, mechanisms, and future perspectives
Antibiotic treatment, the mainstay for the control of bacterial infections, is greatly hampered
by the global prevalence of multidrug-resistant (MDR) bacteria. Photodynamic therapy (PDT) …
by the global prevalence of multidrug-resistant (MDR) bacteria. Photodynamic therapy (PDT) …
Antibody‐incorporated nanomedicines for cancer therapy
Antibody‐based cancer therapy, one of the most significant therapeutic strategies, has
achieved considerable success and progress over the past decades. Nevertheless …
achieved considerable success and progress over the past decades. Nevertheless …
EGFR-targeted photodynamic therapy
L Ulfo, PE Costantini, M Di Giosia, A Danielli… - Pharmaceutics, 2022 - mdpi.com
The epidermal growth factor receptor (EGFR) plays a pivotal role in the proliferation and
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
metastatization of cancer cells. Aberrancies in the expression and activation of EGFR are …
Photosensitizer-functionalized nanocomposites for light-activated cancer theranostics
Photosensitizers (PSs) have received significant attention recently in cancer treatment due
to its theranostic capability for imaging and phototherapy. These PSs are highly responsive …
to its theranostic capability for imaging and phototherapy. These PSs are highly responsive …
Remediating desmoplasia with EGFR‐targeted photoactivable multi‐inhibitor liposomes doubles overall survival in pancreatic cancer
Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …
[HTML][HTML] Recent strides in macromolecular targeted photodynamic therapy for cancer
MB Quaye, G Obaid - Current Opinion in Chemical Biology, 2024 - Elsevier
The recent approval of Akalux® for antibody-targeted photodynamic therapy (PDT) in Japan
(also known as photoimmunotherapy), and the recent approval of Cytalux® for folate …
(also known as photoimmunotherapy), and the recent approval of Cytalux® for folate …
PD‐L1 Immune Checkpoint Targeted Photoactivable Liposomes (iTPALs) Prime the Stroma of Pancreatic Tumors and Promote Self‐Delivery
Desmoplasia in pancreatic ductal adenocarcinoma (PDAC) limits the penetration and
efficacy of therapies. It has been previously shown that photodynamic priming (PDP) using …
efficacy of therapies. It has been previously shown that photodynamic priming (PDP) using …
Progress in nanocarriers codelivery system to enhance the anticancer effect of photodynamic therapy
YL Yang, K Lin, L Yang - Pharmaceutics, 2021 - mdpi.com
Photodynamic therapy (PDT) is a promising anticancer noninvasive method and has great
potential for clinical applications. Unfortunately, PDT still has many limitations, such as …
potential for clinical applications. Unfortunately, PDT still has many limitations, such as …
What NIR photodynamic activation offers molecular targeted nanomedicines: Perspectives into the conundrum of tumor specificity and selectivity
C Bhandari, M Guirguis, NA Savan, N Shrivastava… - Nano Today, 2021 - Elsevier
Near infrared (NIR) photodynamic activation is playing increasingly critical roles in cutting-
edge anti-cancer nanomedicines, which include spatiotemporal control over induction of …
edge anti-cancer nanomedicines, which include spatiotemporal control over induction of …
Spotlight on photoactivatable liposomes beyond drug delivery: an enabler of multitargeting of molecular pathways
The potential of photoactivating certain molecules, photosensitizers (PS), resulting in
photochemical processes, has long been realized in the form of photodynamic therapy …
photochemical processes, has long been realized in the form of photodynamic therapy …