The development of implantable neuroelectrodes is advancing rapidly as these tools are
becoming increasingly ubiquitous in clinical practice, especially for the treatment of …

Highlights•NLRP1 and NLRP3 inflammasome activation is involved in epilepsy
development.•Knockout or knockdown of these molecules improves the symptoms of …

Seizures are life-threatening adverse drug reactions which are investigated late in drug
development using rodent models. Consequently, if seizures are detected, a lot of time …

Background: Epilepsy is a common neurological disease, and neuroinflammation is one of
the main contributors to epileptogenesis. Pyroptosis is a type of pro-inflammatory cell death …

Behçet's syndrome (BS) is a systemic vasculitis with several clinical manifestations.
Neutrophil hyperactivation mediates vascular BS pathogenesis, via both a massive reactive …

Microglia are central nervous system (CNS) resident immune cells that have been
implicated in neuroinflammatory pathogenesis of a variety of neurological conditions. Their …

Aim Nod‐like receptor protein 3 (NLRP3) inflammasome‐mediated inflammation has
emerged as a contributor to epileptogenesis. Endoplasmic reticulum stress (ERS) plays an …

Epilepsy is a chronic brain disease and, considering the amount of people affected of all
ages worldwide, one of the most common neurological disorders. Over 20 novel antiseizure …

Background A hallmark of temporal lobe epilepsy (TLE) is brain inflammation accompanied
by neuronal demise. Accumulating evidence demonstrates that Rev-Erbα is involved in …

In vitro neuronal models have become an important tool to study healthy and diseased
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …