The human vaginal microbiota is a critical determinant of vaginal health. These communities
live in close association with the vaginal epithelium and rely on host tissues for resources …

The vaginal microbiome is an intricate and dynamic microecosystem that constantly
undergoes fluctuations during the female menstrual cycle and the woman's entire life. A …

The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

Bacterial vaginosis (BV) is the most common cause of vaginal discharge. It is associated
with an increased risk of preterm delivery, pelvic inflammatory disease, and an increased …

The microbiome of the female reproductive tract has implications for women's reproductive
health. We examined the vaginal microbiome in two cohorts of women who experienced …

Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. Previous
studies have suggested that the maternal vaginal microbiota contributes to the …

Highlights•Next generation sequencing technologies have enabled large-scale genome
analyses.•Pan-genome analyses provide a framework for predicting and modeling genomic …

The ancient phylum Actinobacteria is composed of phylogenetically and physiologically
diverse bacteria that help Earth's ecosystems function. As free-living organisms and …

Elucidating the cause of bacterial vaginosis has important implications for diagnosis and
treatment. Our current bacterial vaginosis pathogenesis model provides a framework for key …

A healthy female genital tract harbors a microbiome dominated by lactic acid and hydrogen
peroxide producing bacteria, which provide protection against infections by maintaining a …