Infections are a major threat to human reproductive health, and infections in pregnancy can
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …

Diverse inflammatory diseases, infections and malignancies are associated with wasting
syndromes. In many of these conditions, the standards for diagnosis and treatment are …

Toxoplasma gondii is a parasite that infects a wide range of animals and causes zoonotic
infections in humans. Although it normally only results in mild illness in healthy individuals …

Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …

Guanylate-binding proteins (GBPs) have recently emerged as central orchestrators of
immunity to infection, inflammation, and neoplastic diseases. Within numerous host cell …

Dendritic cells (DCs) and macrophages use various receptors to recognize foreign antigens
and to receive feedback control from adaptive immune cells. Although it was long believed …

The guanylate binding protein (GBP) family of interferon‐inducible GTP ases promotes
antimicrobial immunity and cell death. During bacterial infection, multiple mouse Gbps …

Toxoplasma gondii has become a model for studying the phylum Apicomplexa, in part due
to the availability of excellent genetic tools. Although reverse genetic tools are available in a …

Toxoplasma gondii is a protozoan parasite of global importance. In the laboratory setting, T.
gondii is frequently used as a model pathogen to study mechanisms of T helper 1 (TH1) cell …

Toxoplasma gondii is among the most prevalent parasites worldwide, infecting many wild
and domestic animals and causing zoonotic infections in humans. T. gondii differs …