[HTML][HTML] Circulating cell-free nucleic acids: main characteristics and clinical application
Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …
MicroRNA: function, detection, and bioanalysis
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
MicroRNAs in body fluids—the mix of hormones and biomarkers
MA Cortez, C Bueso-Ramos, J Ferdin… - Nature reviews Clinical …, 2011 - nature.com
Since the discovery of microRNAs (miRNAs), the study of these small noncoding RNAs has
steadily increased and more than 10,000 papers have already been published. The great …
steadily increased and more than 10,000 papers have already been published. The great …
Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies
CC Pritchard, E Kroh, B Wood, JD Arroyo… - Cancer prevention …, 2012 - AACR
Circulating, cell-free microRNAs (miRNAs) hold great promise as a new class of cancer
biomarkers due to their surprisingly high stability in plasma, association with disease states …
biomarkers due to their surprisingly high stability in plasma, association with disease states …
[HTML][HTML] Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
[HTML][HTML] microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer
R Cazzoli, F Buttitta, M Di Nicola, S Malatesta… - Journal of thoracic …, 2013 - Elsevier
Introduction: Lung cancer is the highest cause of mortality among tumor pathologies
worldwide. There are no validated techniques for an early detection of pulmonary cancer …
worldwide. There are no validated techniques for an early detection of pulmonary cancer …
Extracellular microRNA: a new source of biomarkers
MicroRNAs (miRNAs) are a recently discovered class of small, non-coding RNAs that
regulate protein levels post-transcriptionally. miRNAs play important regulatory roles in …
regulate protein levels post-transcriptionally. miRNAs play important regulatory roles in …
[HTML][HTML] Expression of the long non-coding RNA HOTAIR correlates with disease progression in bladder cancer and is contained in bladder cancer patient urinary …
Exosomes are 30-150nM membrane-bound secreted vesicles that are readily isolated from
biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA) …
biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA) …
[HTML][HTML] New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
the monitoring of treatment, something that is often difficult to achieve using standard tissue …