Complex functioning of the genome in the cell nucleus is controlled at different levels:(a) the
DNA base sequence containing all relevant inherited information;(b) epigenetic pathways …

Simple Summary Many types of cancer cells utilize the common amino acid l-glutamine to
maintain their metabolic demands for energy and the nitrogen required for DNA synthesis …

In the present review, we concentrated on primary signaling and regulatory events in plant
cells that are rapidly evoked in response to extracellular polyamines in vivo and induce …

Background It is becoming clearer that living cells use water/water (w/w) phase separation to
form membraneless organelles that exhibit various important biological functions. Currently …

Cell-free gene expression systems have been valuable tools for understanding how
transcription/translation can be regulated in living cells. Many studies have investigated the …

Hydroxyurea (HU; hydroxycarbamide) is a chemotherapy medication used to treat various
types of cancer and other diseases such as sickle cell anemia. HU inhibits DNA synthesis by …

Alcohols are used in the life sciences because they can condense and precipitate DNA.
Alcohol consumption has been linked to many diseases and can alter genetic activity. In the …

The effect of monovalent cations on a cell‐free transcription–translation (TX–TL) system is
examined using a luciferase assay. It is found that the potency for all ions analyzed here is in …

By adapting the method of single molecular observation for individual DNAs, it will be shown
that reliable analysis of double-strand breaks, DSBs, becomes possible for various kinds of …