Advancing cell therapy for neurodegenerative diseases

S Temple - Cell stem cell, 2023 - cell.com
Cell-based therapies are being developed for various neurodegenerative diseases that
affect the central nervous system (CNS). Concomitantly, the roles of individual cell types in …

Umbilical cord blood derived cell expansion: a potential neuroprotective therapy

TR Penny, G Jenkin, SL Miller… - Stem Cell Research & …, 2024 - Springer
Umbilical cord blood (UCB) is a rich source of beneficial stem and progenitor cells with
known angiogenic, neuroregenerative and immune-modulatory properties. Preclinical …

Combination therapy with Treg and mesenchymal stromal cells enhances potency and attenuation of inflammation after traumatic brain injury compared to …

HW Caplan, KS Prabhakara, NE Toledano Furman… - Stem …, 2021 - academic.oup.com
The inflammatory response after traumatic brain injury (TBI) can lead to significant
secondary brain injury and chronic inflammation within the central nervous system. Cell …

Human cord blood-derived regulatory T-cell therapy modulates the central and peripheral immune response after traumatic brain injury

HW Caplan, KS Prabhakara, A Kumar… - Stem Cells …, 2020 - academic.oup.com
Traumatic brain injury (TBI) causes a profound inflammatory response within the central
nervous system and peripheral immune system, which contributes to secondary brain injury …

Determining sex-based differences in inflammatory response in an experimental traumatic brain injury model

MC Scott, KS Prabhakara, AJ Walters… - Frontiers in …, 2022 - frontiersin.org
Introduction Traumatic brain injury is a leading cause of injury-related death and morbidity.
Multiple clinical and pre-clinical studies have reported various results regarding sex-based …

Recent advances in the treatment of traumatic brain injury with autologous and non-autologous multipotent stem and progenitor cells: preclinical models and clinical …

M Alizada, S Lin, H Gao - Folia Neuropathologica, 2021 - termedia.pl
Traumatic brain injury (TBI) is a global health issue which causes millions of deaths and
disabilities every year. The survivors of TBI may suffer from sensorimotor dysfunction …

Umbilical cord blood cells for the treatment of preterm white matter injury: Potential effects and treatment options

H Qiu, T Qian, T Wu, X Wang, C Zhu… - Journal of …, 2021 - Wiley Online Library
Preterm birth is a global public health problem. A large number of preterm infants survive
with preterm white matter injury (PWMI), which leads to neurological deficits, and has …

Пуповинна кров як коректор гематологічних і цитоморфологічних характеристик лімфогемопоетичних органів при експериментальному атопічному дерматиті

H Koval, M Bondarovych, A Goltsev - Innovative Biosystems and …, 2023 - ibb.kpi.ua
Background. Atopic dermatitis (AD) is an inflammatory skin disease caused by a shift in the
interaction between cells of the immune system and the skin. Steroid anti-inflammatory …

[HTML][HTML] Combination therapy with Treg and MSC enhances potency and attenuation of inflammation after traumatic brain injury compared to monotherapy

HW Caplan, KS Prabhakara… - Stem cells (Dayton …, 2021 - ncbi.nlm.nih.gov
The inflammatory response after traumatic brain injury (TBI) can lead to significant
secondary brain injury and chronic inflammation within the central nervous system (CNS) …

The Development of Stem Cell-Based Treatment for Acute Ischemic Cerebral Injury

X Bai, J Xu, T Zhu, Y He, H Zhang - Current stem cell research …, 2020 - ingentaconnect.com
Acute ischemic brain injury is a serious disease that severely endangers the life safety of
patients. Such disease is hard to predict and highly lethal with very limited effective …