Abstract Serotonin (5-HT), a well-known neurotransmitter in the brain, also plays an
important role in peripheral tissues, including the immune system. There is a growing body …

Platelets are anucleate blood cells that play a crucial role in the maintenance of hemostasis.
While platelet activation and elevated platelet counts (thrombocytosis) are associated with …

Non-alcoholic fatty liver disease ranges from steatosis to non-alcoholic steatohepatitis
(NASH), potentially progressing to cirrhosis and hepatocellular carcinoma (HCC). Here, we …

Platelet-derived peripheral serotonin has pleiotropic effects on coagulation, metabolism,
tissue regeneration, and cancer growth; however, the effect of serotonin on the tumor …

Blood platelets have long been recognised to bring about primary haemostasis with
deficiencies in platelet production and function manifesting in bleeding while upregulated …

Abstract Serotonin or 5‐hydroxytryptamine (5‐HT) is a neurotransmitter and hormone that
contributes to the regulation of various physiological functions by its actions in the central …

Summary Effector CD8+ T cells (CD8 TE) play a key role during hepatotropic viral infections.
Here, we used advanced imaging in mouse models of hepatitis B virus (HBV) pathogenesis …

Liver fibrosis is a dynamic wound-healing process characterized by the net accumulation of
extracellular matrix. There is no efficient antifibrotic therapy other than liver transplantation to …

Platelets contribute to processes beyond thrombus formation and may play a so far
underestimated role as an immune cell in various circumstances. This review outlines …

In recent years, various studies have increasingly explained platelet functions not only in
their central role as a regulator in cellular hemostasis and coagulation. In fact, there is …