Abstract Changes in muscle mass may result from changes in protein turnover, reflecting the
balance between protein synthesis and protein degradation, and changes in cell turnover …

In mammalian systems, skeletal muscle exists in a dynamic state that monitors and regulates
the physiological investment in muscle size to meet the current level of functional demand …

There is currently an unmet need for the supply of autologous, patient-specific stem cells for
regenerative therapies in the clinic. Mesenchymal stem cell differentiation can be driven by …

Oligonucleotide‐based hepatocyte growth factor (HGF) mimetics are described. A DNA
aptamer to Met, a cognate receptor for HGF, was shown to induce Met activation when used …

The size of in vitro engineered skeletal muscle tissue is limited due to the lack of a vascular
network in vitro. In this article, we report tissue-engineered skeletal muscle consisting of …

Bone and muscle have been recognized as endocrine organs since they produce and
secrete “hormone-like factors” that can mutually influence each other and other tissues …

The anti-inflammatory agents glucocorticoids (GC) are the only available treatment for
Duchenne muscular dystrophy (DMD). However, long-term GC treatment causes muscle …

Designing synthetic surrogates of functional proteins is an important, albeit challenging, task
in the field of chemistry. A strategy toward the design of synthetic agonists for growth factor …

Satellite cells are unipotent stem cells involved in muscle regeneration. However, the
skeletal muscle microenvironment exerts a dominant influence over stem cell function. The …

Skeletal muscle mass is determined by the net dynamic balance between protein synthesis
and degradation. Although the Akt/mechanistic target of rapamycin (mTOR)-dependent …