In the past decade, evidence for a fluid clearance pathway in the central nervous system
known as the glymphatic system has grown. According to the glymphatic system concept …

Transient or permanent loss of tissue perfusion due to ischaemic stroke can lead to damage
to the neurovasculature, and disrupt brain homeostasis, causing long-term motor and …

Aquaporins facilitate the passive transport of water, solutes, or ions across biological
membranes. They are implicated in diverse pathologies including brain edema following …

The aquaporins (AQPs) are a family of small, integral membrane proteins that facilitate water
transport across the plasma membranes of cells in response to osmotic gradients. Data from …

ABSTRACT Introduction: Aquaporin-4 (AQP4) is a water transporting protein expressed at
the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis …

✓ Cerebral edema is caused by a variety of pathological conditions that affect the brain. It is
associated with two separate pathophysiological processes with distinct molecular and …

Aquaporins (AQPs) are water channel proteins that are essential to life, being expressed in
all kingdoms. In humans, there are 13 AQPs, at least one of which is found in every organ …

Aquaporin (AQP) 4 is the predominant water channel in the mammalian brain, abundantly
expressed in the blood–brain and brain–cerebrospinal fluid interfaces of glial cells. Its …

The glymphatic system is a unique pathway that utilises end-feet Aquaporin 4 (AQP4)
channels within perivascular astrocytes, which is believed to cause cerebrospinal fluid …

The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …