Efficient immune responses against invading pathogens often involve coordination between
cells from both the innate and adaptive immune systems. For multiple decades, it has been …

Human cytomegalovirus (HCMV) is a highly prevalent herpesvirus that can cause severe
disease in immunocompromised individuals and immunologically immature fetuses and …

Most tissues are populated by tissue-resident memory T cells (TRM cells), which are
adapted to their niche and appear to be indispensable for local protection against …

T cell responses are critical for controlling cytomegalovirus (CMV) infection. However, CMV
expresses immune evasion genes promoting escape from T cell immunity. Furthermore …

Neuroanatomical barriers with physical, chemical, and immunological properties play an
essential role in preventing the spread of peripheral infections into the CNS. A failure to …

Tissue‐resident memory T cells (TRMs) are plentiful in the memory T cell pool and persist in
barrier sites without recirculating. Increasing evidence has shown that some kinds of CD8+ …

Recent evidence has shown that neuroinflammation plays a key role in the pathogenesis of
Parkinson's disease (PD). However, different components of the brain's immune system may …

The neurodevelopmental defects associated with ZIKV infections early in pregnancy are well
documented, however the potential defects and long-term consequences associated with …

The contribution of circulating verses tissue resident memory T cells (TRMs) to clinical
neuropathology is an enduring question due to a lack of mechanistic insights. The prevailing …

Congenital human cytomegalovirus (cHCMV) infection of the brain is associated with a wide
range of neurocognitive sequelae. Using infection of newborn mice with mouse …