Hexokinase II is often highly expressed in poorly differentiated and rapidly growing tumors
that exhibit a high rate of aerobic glycolysis. Hexokinase II binds to the mitochondrial …

Mitochondrial respiratory chain diseases are a highly diverse group of disorders whose
main unifying characteristic is the impairment of mitochondrial function. As befits an …

Like in chemical catalysis, there is a clear trend in biocatalysis to carry out synthetic
transformations at the manufacturing scale heterogeneously catalyzed. Recycling of …

We have developed a method for measuring the local concentration of ATP at the
extracellular surface of live cells. This method relies on the specific attachment to the cell …

This review focuses on problems of the intracellular regulation of mitochondrial function in
the brain via the (i) supply of mitochondria with ADP by means of ADP shuttles and channels …

The effect of increasing trehalose concentrations on the kinetics of the plasma membrane
H+-ATPase from Kluyveromyces lactis was studied at different temperatures. At 20° C …

In a previous study, we presented evidence for the existence of a nucleotide‐binding site
(NBS) in the N‐terminal region of the voltage‐dependent anion channel (VDAC1). In this …

Insulin‐producing pancreatic β cells are functionally impaired or destroyed in diabetes
mellitus. The onset of type 1 diabetes (T1D) represents the culmination of a prolonged …

Heterologous binding of rat brain hexokinase to wild type, porinless, and recombinant yeast
mitochondria expressing human porin was assessed, partially characterized, and compared …

The association of rat brain hexokinase with heterologous recombinant yeast mitochondria
harboring human porin (Yh) is comparable to that with rat liver mitochondria in terms of …