S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca2+ homeostasis …

Since its discovery in 1992, the small, 10.4 kDa calcium-binding protein S100P has gained
the attention of researchers from different scientific fields due to its potential roles in both …

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with low survival rates.
Current therapeutic treatments have very poor response rates due to the high inherent …

S100P, a calcium-binding protein, is known to advance tumor progression and metastasis in
pancreatic and several other cancers. Herein is described the in silico identification of a …

S100 proteins are members of the superfamily of Ca 2+-binding proteins characterized by
the specific Ca 2+-binding motif, the EF-hand. Proteins of this superfamily are of clinical use …

A multitude of Ca 2+-sensor proteins containing the specific Ca 2+-binding motif (helix-loop-
helix, called EF-hand) are of major clinical relevance in a many human diseases …

S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca (2)+ …

Natural products have always served as an important source of drugs for treating various
diseases. Among various privileged natural product scaffolds, the benzopyrone class of …

There are currently still no approved antiviral drugs to treat or prevent chikungunya virus
(CHIKV) infections despite the fact that this arbovirus continues to cause outbreaks in Africa …

Pancreatic cancer remains a disease that is very difficult to treat. S100 proteins are small
calcium binding proteins with diverse intra-and extracellular functions that modulate different …