From basics to clinical: a comprehensive review on spinal cord injury

NA Silva, N Sousa, RL Reis, AJ Salgado - Progress in neurobiology, 2014 - Elsevier
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

CART in the brain of vertebrates: circuits, functions and evolution

NK Subhedar, KT Nakhate, MA Upadhya, DM Kokare - Peptides, 2014 - Elsevier
Cocaine-and amphetamine-regulated transcript peptide (CART) with its wide distribution in
the brain of mammals has been the focus of considerable research in recent years. Last two …

[HTML][HTML] Plumbagin ameliorates memory dysfunction in streptozotocin induced Alzheimer's disease via activation of Nrf2/ARE pathway and inhibition of β-secretase

KT Nakhate, AP Bharne, VS Verma, DN Aru… - Biomedicine & …, 2018 - Elsevier
Abstract Although plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) protects against
cerebral ischemia and spinal cord injury-induced oxidative stress and inflammation by …

Influence of bisphenol A and its analog bisphenol S on cocaine-and amphetamine-regulated transcript peptide–positive enteric neurons in the mouse gastrointestinal …

K Makowska, KRC Fagundes… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction Bisphenol A (BPA) is used in large quantities for the production of plastics and
is present in various everyday objects. It penetrates living organisms and shows …

MANF attenuates neuronal apoptosis and promotes behavioral recovery via Akt/MDM‐2/p53 pathway after traumatic spinal cord injury in rats

L Gao, W Xu, S Fan, T Li, T Zhao, G Ying, J Zheng… - Biofactors, 2018 - Wiley Online Library
The aim of this study was to investigate the potential effect and mechanism of action of
MANF in attenuating neuronal apoptosis following t‐SCI. A clip compressive model was …

Tegaserod, a small compound mimetic of polysialic acid, promotes functional recovery after spinal cord injury in mice

HC Pan, YQ Shen, G Loers, I Jakovcevski… - Neuroscience, 2014 - Elsevier
In a previous study, we have shown that the small organic compound tegaserod, a drug
approved for clinical application in an unrelated condition, is a mimic of the regeneration …

Oral administration of α-Asarone promotes functional recovery in rats with spinal cord injury

MJ Jo, H Kumar, HP Joshi, H Choi, WK Ko… - Frontiers in …, 2018 - frontiersin.org
α-asarone, a bioactive compound found in Acorus plant species, has been shown to exhibit
neuroprotective, anti-oxidative, anti-inflammatory, and cognitive-enhancing effects …

Neuroprotective effect of agmatine in mouse spinal cord injury model: Modulation by imidazoline receptors

M DIxit, M Upadhya, B Taksande… - Journal of Natural …, 2018 - publications.aston.ac.uk
Objective: The involvement of imidazoline receptors in the effect of agmatine was studied in
locomotor recovery following experimental SCI (ESCI) in mice. Methods: ESCI was induced …

Assessment of the Neuroprotective Effects of Lavandula angustifolia Extract on the Contusive Model of Spinal Cord Injury in Wistar Rats

G Kaka, K Yaghoobi, S Davoodi, SR Hosseini… - Frontiers in …, 2016 - frontiersin.org
Introduction: Spinal cord injury (SCI) involves a primary trauma and secondary cellular
processes that can lead to severe damage to the nervous system, resulting in long-term …

Cardiovascular autonomic dysfunction: link between multiple sclerosis osteoporosis and neurodegeneration

Z Sternberg - Neuromolecular Medicine, 2018 - Springer
The high prevalence of osteoporosis, observed in multiple sclerosis (MS) patients, has been
attributed to reduced mobility and or the use of disease-modifying drugs. However, MS …