[HTML][HTML] The long road toward COVID-19 herd immunity: vaccine platform technologies and mass immunization strategies
LSF Frederiksen, Y Zhang, C Foged… - Frontiers in …, 2020 - frontiersin.org
There is an urgent need for effective countermeasures against the current emergence and
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …
accelerating expansion of coronavirus disease 2019 (COVID-19), caused by severe acute …
[HTML][HTML] Malaria vaccines since 2000: progress, priorities, products
PE Duffy, J Patrick Gorres - npj Vaccines, 2020 - nature.com
Malaria vaccine development entered a new era in 2015 when the pre-erythrocytic
Plasmodium falciparum candidate RTS, S was favorably reviewed by the European …
Plasmodium falciparum candidate RTS, S was favorably reviewed by the European …
Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
[HTML][HTML] The continued advance of vaccine adjuvants–'we can work it out'
In the last decade there have been some significant advances in vaccine adjuvants,
particularly in relation to their inclusion in licensed products. This was proceeded by several …
particularly in relation to their inclusion in licensed products. This was proceeded by several …
Current status of COVID‐19 (pre) clinical vaccine development
T Ye, Z Zhong, A García‐Sastre… - Angewandte Chemie …, 2020 - Wiley Online Library
The current COVID‐19 pandemic has a tremendous impact on daily life world‐wide. Despite
the ability to dampen the spread of SARS‐CoV‐2, the causative agent of the diseases …
the ability to dampen the spread of SARS‐CoV‐2, the causative agent of the diseases …
[HTML][HTML] Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
MD Larsen, M Lopez-Perez, EK Dickson… - Nature …, 2021 - nature.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …
Current approaches to malaria vaccines
PE Duffy - Current opinion in microbiology, 2022 - Elsevier
Highlights•First malaria vaccine RTS, S induces anti-sporozoite antibodies to protect
children.•Whole-sporozoite vaccines induce T cells and antibodies and confer field …
children.•Whole-sporozoite vaccines induce T cells and antibodies and confer field …
PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study
SB Sirima, L Richert, A Chêne, AT Konate… - The Lancet Infectious …, 2020 - thelancet.com
Background PRIMVAC is a VAR2CSA-derived placental malaria vaccine candidate aiming
to prevent serious clinical outcomes of Plasmodium falciparum infection during pregnancy …
to prevent serious clinical outcomes of Plasmodium falciparum infection during pregnancy …
New insights into malaria pathogenesis
Malaria remains a major public health threat in tropical and subtropical regions across the
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …
world. Even though less than 1% of malaria infections are fatal, this leads to about 430,000 …
[HTML][HTML] Poor birth outcomes in malaria in pregnancy: recent insights into mechanisms and prevention approaches
Pregnant women in malaria-endemic regions are susceptible to malaria in pregnancy, which
has adverse consequences on birth outcomes, including having small for gestational age …
has adverse consequences on birth outcomes, including having small for gestational age …