Aplastic anemia (AA), a rare but potentially life-threatening disease, is a paradigm of bone
marrow failure syndromes characterized by pancytopenia in the peripheral blood and …

Background In most patients with aplastic anemia (AA), the diagnosis is limited to a
description of the symptoms. Lack of understanding of the underlying pathophysiological …

Immune-mediated hematopoietic destruction is a key factor in idiopathic severe aplastic
anemia (SAA). With great immunomodulatory functions, mesenchymal stem cells (MSCs) …

We conducted a phase II, noncomparative, multicenter study to assess the efficacy and
safety of allogeneic bone marrow-derived mesenchymal stromal cells (BM-MSCs) expanded …

Abstract Background Mesenchymal stem cells (MSCs) are a class of adult stem cells with
self-renewal and multidirectional differentiation potential that may be a treatment for aplastic …

Abstract Background Anti-thymoglobulin (ATG)-based immunosuppressive treatment (IST) is
the standard first-line management for patients with severe AA/very severe AA (SAA/VSAA) …

Background Bone marrow mesenchymal stem cells (BM-MSC) are an integral part of the BM
niche that is essential to maintain hematopoietic homeostasis. In aplastic anemia (AA), a few …

Tissue engineering technologies offer new treatment strategies for the repair of peripheral
nerve injury, but cell loss between seeding and adhesion to the scaffold remains inevitable …

Background and Objective. Acquired aplastic anemia (aAA) is a bone marrow failure
disorder characterized by pancytopenia and bone marrow aplasia. Bone marrow …

Aplastic anemia (AA) is a bone marrow failure syndrome with high morbidity and mortality.
Bone marrow (BM)‑mesenchymal stem cells (MSCs) are the main components of the BM …