[HTML][HTML] Large animal models in regenerative medicine and tissue engineering: to do or not to do

I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020 - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

The tissue-engineered vascular graft—past, present, and future

S Pashneh-Tala, S MacNeil… - Tissue Engineering Part B …, 2016 - liebertpub.com
Cardiovascular disease is the leading cause of death worldwide, with this trend predicted to
continue for the foreseeable future. Common disorders are associated with the stenosis or …

Bioengineering human tissues and the future of vascular replacement

KM Naegeli, MH Kural, Y Li, J Wang… - Circulation …, 2022 - Am Heart Assoc
Cardiovascular defects, injuries, and degenerative diseases often require surgical
intervention and the use of implantable replacement material and conduits. Traditional …

[HTML][HTML] Current strategies for the manufacture of small size tissue engineering vascular grafts

M Carrabba, P Madeddu - Frontiers in bioengineering and …, 2018 - frontiersin.org
Occlusive arterial disease, including coronary heart disease (CHD) and peripheral arterial
disease (PAD), is the main cause of death, with an annual mortality incidence predicted to …

[HTML][HTML] Polyhydroxyalkanoates in tissue repair and regeneration

W Guo, K Yang, X Qin, R Luo, H Wang… - Engineered …, 2022 - Elsevier
Developing advanced biocompatibility materials is of critical importance in biomedical
engineering. Polyhydroxyalkanoates (PHA), being famous for its flexible mechanical …

Long term performance of polycaprolactone vascular grafts in a rat abdominal aorta replacement model

S de Valence, JC Tille, D Mugnai, W Mrowczynski… - Biomaterials, 2012 - Elsevier
In the active field of vascular graft research, polycaprolactone is often used because of its
good mechanical strength and its biocompatibility. It is easily processed into micro and nano …

Spontaneous reversal of stenosis in tissue-engineered vascular grafts

JD Drews, VK Pepper, CA Best, JM Szafron… - Science translational …, 2020 - science.org
We developed a tissue-engineered vascular graft (TEVG) for use in children and present
results of a US Food and Drug Administration (FDA)–approved clinical trial evaluating this …

[HTML][HTML] Systematic review of tissue-engineered vascular grafts

D Durán-Rey, V Crisóstomo… - … in bioengineering and …, 2021 - frontiersin.org
Pathologies related to the cardiovascular system are the leading causes of death worldwide.
One of the main treatments is conventional surgery with autologous transplants. Although …

[HTML][HTML] Acellular tissue-engineered vascular grafts from polymers: Methods, achievements, characterization, and challenges

X Wang, V Chan, PR Corridon - Polymers, 2022 - mdpi.com
Extensive and permanent damage to the vasculature leading to different pathogenesis calls
for developing innovative therapeutics, including drugs, medical devices, and cell therapies …

Review of vascular graft studies in large animal models

RH Liu, CS Ong, T Fukunishi, K Ong… - Tissue Engineering Part …, 2018 - liebertpub.com
As the incidence of cardiovascular disease continues to climb worldwide, there is a
corresponding increase in demand for surgical interventions involving vascular grafts. The …