The integrated brain network that controls respiration
F Krohn, M Novello, RS van der Giessen, CI De Zeeuw… - Elife, 2023 - elifesciences.org
Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …
Breathing rhythm and pattern and their influence on emotion
Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain
and body. The apparent simplicity of breathing belies a complex neural control system, the …
and body. The apparent simplicity of breathing belies a complex neural control system, the …
Advancing respiratory–cardiovascular physiology with the working heart–brainstem preparation over 25 years
Twenty‐five years ago, a new physiological preparation called the working heart–brainstem
preparation (WHBP) was introduced with the claim it would provide a new platform allowing …
preparation (WHBP) was introduced with the claim it would provide a new platform allowing …
Differential contribution of the retrotrapezoid nucleus and C1 neurons to active expiration and arousal in rats
GMPR Souza, RL Stornetta, DS Stornetta… - Journal of …, 2020 - Soc Neuroscience
Collectively, the retrotrapezoid nucleus (RTN) and adjacent C1 neurons regulate breathing,
circulation and the state of vigilance, but previous methods to manipulate the activity of these …
circulation and the state of vigilance, but previous methods to manipulate the activity of these …
Interaction between the retrotrapezoid nucleus and the parafacial respiratory group to regulate active expiration and sympathetic activity in rats
The retrotrapezoid nucleus (RTN) contains chemosensitive cells that distribute CO2-
dependent excitatory drive to the respiratory network. This drive facilitates the function of the …
dependent excitatory drive to the respiratory network. This drive facilitates the function of the …
Interdependent feedback regulation of breathing by the carotid bodies and the retrotrapezoid nucleus
PG Guyenet, DA Bayliss, RL Stornetta… - The Journal of …, 2018 - Wiley Online Library
The retrotrapezoid nucleus (RTN) regulates breathing in a CO2‐and state‐dependent
manner. RTN neurons are glutamatergic and innervate principally the respiratory pattern …
manner. RTN neurons are glutamatergic and innervate principally the respiratory pattern …
The parafacial respiratory group and the control of active expiration
A Pisanski, S Pagliardini - Respiratory Physiology & Neurobiology, 2019 - Elsevier
Breathing at rest is typically characterized by three phases: active inspiration, post-
inspiration (or stage 1 expiration), and passive expiration (or stage 2 expiration). Breathing …
inspiration (or stage 1 expiration), and passive expiration (or stage 2 expiration). Breathing …
Disordered breathing in a Pitt-Hopkins syndrome model involves Phox2b-expressing parafacial neurons and aberrant Nav1. 8 expression
Pitt-Hopkins syndrome (PTHS) is a rare autism spectrum-like disorder characterized by
intellectual disability, developmental delays, and breathing problems involving episodes of …
intellectual disability, developmental delays, and breathing problems involving episodes of …
Inhibitory control of active expiration by the Bötzinger complex in rats
KC Flor, WH Barnett, M Karlen‐Amarante… - The Journal of …, 2020 - Wiley Online Library
Key points Contraction of abdominal muscles at the end of expiration during metabolic
challenges (such as hypercapnia and hypoxia) improves pulmonary ventilation. The …
challenges (such as hypercapnia and hypoxia) improves pulmonary ventilation. The …
The Kölliker-Fuse nucleus orchestrates the timing of expiratory abdominal nerve bursting
WH Barnett, SEM Jenkin, WK Milsom… - Journal of …, 2018 - journals.physiology.org
Coordination of respiratory pump and valve muscle activity is essential for normal breathing.
A hallmark respiratory response to hypercapnia and hypoxia is the emergence of active …
A hallmark respiratory response to hypercapnia and hypoxia is the emergence of active …