In agonising, crippling pain from lung cancer, Mr S came to the palliative care service in
Calicut, Kerala, from an adjoining district a couple of hours away by bus. His body language …

Background: The management of acute and chronic pain for individuals living with sickle cell
disease (SCD) is a clinical challenge. This reflects the paucity of clinical SCD pain research …

This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

There have been some modest recent advancements in the research of Complex Regional
Pain Syndrome, yet the amount and quality of the work in this complicated multifactorial …

We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

Background: Prescription opioid–related overdose deaths increased sharply during 1999–
2010 in the United States in parallel with increased opioid prescribing. CDC assessed …

Worldwide, the use of prescription opioid analgesics more than doubled between 2001 and
2013, with several countries, including the USA, Canada, and Australia, experiencing …

Importance Primary care clinicians find managing chronic pain challenging. Evidence of
long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious …

Background: In response to adverse outcomes from prescription opioids, the Centers for
Disease Control and Prevention (CDC) released the Guideline for Prescribing Opioids for …

Methods In developing this guideline, the steering committee followed standards for
trustworthy guidelines. 15 We included innovative approaches for key standards such as …