Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor
vascularized, and its low cell density allows only extremely limited self-renewal. Most clinical …

Cell-based therapy represents a promising treatment strategy for cartilage defects. Alone or
in combination with scaffolds/biological signals, these strategies open many new avenues …

Osteoarthritis (OA) is a common chronic disease and a significant health concern that needs
to be urgently solved. OA affects the cartilage and entire joint tissues, including the …

For successful tracheal reconstruction, tissue-engineered artificial trachea should meet
several requirements, such as biocompatible constructs comparable to natural trachea …

Osteoarthritis (OA) is a chronic disease mainly characterized by degenerative changes in
cartilage, but other joint elements such as bone are also affected. To date, there are no …

Tissue engineering potentially offers new treatments for disorders of the temporomandibular
joint which frequently afflict patients. Damage or disease in this area adversely affects …

The process of cartilage destruction in the diarthrodial joint is progressive and irreversible.
This destruction is extremely difficult to manage and frustrates researchers, clinicians, and …

Effective early disease modifying options for osteoarthritis remain lacking. Tissue
engineering approach to generate cartilage in vitro has emerged as a promising option for …

The development of induced pluripotent stem cells has brought unlimited possibilities to the
field of regenerative medicine. This could be ideal for treating osteoarthritis and other …

Due to the restricted intrinsic capacity of resident chondrocytes to regenerate the lost
cartilage postinjury, stem cell‐based therapies have been proposed as a novel therapeutic …