The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Upregulation of sialyltransferases—the enzymes responsible for the addition of sialic acid to
growing glycoconjugate chains—and the resultant hypersialylation of up to 40–60% of …

Recent biomedical discoveries have revolutionized the concept and understanding of
carcinogenesis, a complex and multistep phenomenon which involves accretion of genetic …

Over the last decades, the cancer survival rate has increased due to personalized therapies,
the discovery of targeted therapeutics and novel biological agents, and the application of …

Cancer stem cells (CSCs), the subpopulation of cancer cells, have the capability of
proliferation, self-renewal, and differentiation. The presence of CSCs is a key factor leading …

Cancer stem-like cells (CSCs), a subpopulation of cancer cells, possess remarkable
capability in proliferation, self-renewal, and differentiation. Their presence is recognized as a …

Cancer stem cells (CSCs) or tumor‐initiating cells (TICs) as a small subset of neoplastic
cells are able to produce a tumor (tumorigenesis), maintain the population of tumorigenic …

Gastric cancer (GC) was the fourth deadliest cancer in the world in 2020, and about 770,000
people died from GC that year. The death of patients with GC is mainly caused by the …

Gastric cancer stem cells (GCSCs) play critical roles in gastric cancer (GC) initiation and
development. Circular RNAs (circRNAs) participate in diverse cancer biological processes …

Cancer biology research over recent decades has given ample evidence for the existence of
self-renewing and drug-resistant populations within heterogeneous tumors, widely …