[HTML][HTML] Molecular insights into coumarin analogues as antimicrobial agents: Recent developments in drug discovery

RS Cheke, HM Patel, VM Patil, IA Ansari, JP Ambhore… - Antibiotics, 2022 - mdpi.com
Simple Summary Coumarins are a large family of benzopyrones, and more than 1300
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …

[HTML][HTML] Comparative study of the synthetic approaches and biological activities of the bioisosteres of 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles over the past decade

RM El-Masry, HH Kadry, AT Taher, SM Abou-Seri - Molecules, 2022 - mdpi.com
The bioisosteres of 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles are well-known
pharmacophores for many medicinally important drugs. Throughout the past 10 years, 1, 3, 4 …

Novel hybrids of benzothiazole-1, 3, 4-oxadiazole-4-thiazolidinone: Synthesis, in silico ADME study, molecular docking and in vivo anti-diabetic assessment

R Bhutani, DP Pathak, G Kapoor, A Husain… - Bioorganic chemistry, 2019 - Elsevier
A series of new benzothiazole-1, 3, 4-oxadiazole-4-thiazolidinone hybrid analogs (Tz1-
Tz28) were synthesized in search of potential anti-diabetic agents. Molecular docking study …

Synthesis of novel benzodioxane midst piperazine moiety decorated chitosan silver nanoparticle against biohazard pathogens and as potential anti-inflammatory …

CS Karthik, HM Manukumar, AP Ananda… - International journal of …, 2018 - Elsevier
Nanoparticles (NPs) are currently being investigated along with the use of biodegradable
polymer containing active agents in many areas of medicine for targeted applications. The …

[HTML][HTML] Design and synthesis of coumarin-triazole hybrids: biocompatible anti-diabetic agents, in silico molecular docking and ADME screening

VC Basappa, VH Kameshwar, K Kumara, DK Achutha… - Heliyon, 2020 - cell.com
The current study demonstrates the synthesis of coumarin-triazole hybrids 8 (ae) in four
steps starting from substituted salicylaldehyde 1 (ae), and diethyl malonate 2. The …

[HTML][HTML] Antibacterial Effect of 16 Essential Oils and Modulation of mex Efflux Pumps Gene Expression on Multidrug-Resistant Pseudomonas aeruginosa Clinical …

RL Coșeriu, C Vintilă, M Pribac, AD Mare, CN Ciurea… - Antibiotics, 2023 - mdpi.com
The purpose of the study was to describe the antimicrobial activity of 16 common essential
oils (EOs) on multidrug-resistant (MDR) Pseudomonas aeruginosa clinical isolates …

Synthesis, characterization, crystal structure, Hirshfeld surface analysis, antioxidant properties and DFT calculations of a novel pyrazole derivative: ethyl 1-(2, 4 …

S Naveen, K Kumara, AD Kumar, KA Kumar… - Journal of Molecular …, 2021 - Elsevier
An effective route for the direct synthesis of substituted pyrazole through 3+ 2 annulation
method was described.(E)-ethyl 2-benzylidene-3-oxobutanoate was prepared from ethyl …

[HTML][HTML] Design, Synthesis, Molecular Modeling and Biological Evaluation of Novel Pyrazole Benzimidazolone Derivatives as Potent Antioxidants

M Adardour, M Ait Lahcen, M Oubahmane, W Ettahiri… - Pharmaceuticals, 2023 - mdpi.com
In the present study, we used benzimidazolone as a starting material to efficiently synthesize
several hybrid compounds of pyrazole benzimidazolone derivatives by the 1, 3-dipolar …

Synthesis and Characterization of Cobalt (III) and Copper (II) Complexes of 2‐((E)‐(6‐Fluorobenzo [d] thiazol‐2‐ylimino) methyl)‐4‐chlorophenol: DNA Binding and …

K Savithri, BCV Kumar, HK Vivek… - International Journal …, 2018 - Wiley Online Library
A bidentate (N‐and O‐) imine‐based ligand (L1) and its metal complexes of types [CuII (L1)
2](C1),[CuII (L1)(Phen)](C2),[CoIII (L1) 2](C3), and [CoIII (L1)(Phen)](C4)(L1= 2‐((E)‐(6 …

Synthesis, characterization and antioxidant activity studies of new coumarin tethered 1, 3, 4-oxadiazole analogues

VC Basappa, S Penubolu, DK Achutha… - Journal of Chemical …, 2021 - Springer
The present work describes the synthesis of a series of substituted 3-(5-phenyl-1, 3, 4-
oxadiazol-2-yl)-2 H-chromen-2-ones 7 (a–j) using substituted aldehydes with analogues of …