Regulation of ferroptosis by PI3K/Akt signaling pathway: a promising therapeutic axis in cancer

H Su, C Peng, Y Liu - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
The global challenge posed by cancer, marked by rising incidence and mortality rates,
underscores the urgency for innovative therapeutic approaches. The PI3K/Akt signaling …

Circular RNAs in the KRAS pathway: Emerging players in cancer progression

MS Hussain, E Moglad, M Afzal, P Bansal… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) have been recognized as key components in the intricate
regulatory network of the KRAS pathway across various cancers. The KRAS pathway, a …

Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer

MS Hussain, E Moglad, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Circular RNAs (circRNAs) constitute a recently identified category of closed continuous loop
RNA transcripts, serving as a subset of competing endogenous RNAs (ceRNAs) with the …

[HTML][HTML] Unveiling the potential effects of resveratrol in lung cancer treatment: Mechanisms and nanoparticle-based drug delivery strategies

B Najafiyan, ZB Hosseini, S Esmaelian… - Biomedicine & …, 2024 - Elsevier
Lung cancer ranks among the most prevalent forms of cancer and remains a significant
factor in cancer-related mortality across the world. It poses significant challenges to …

The progressive trend of modeling and drug screening systems of breast cancer bone metastasis

H Kolahi Azar, M Gharibshahian, M Rostami… - Journal of Biological …, 2024 - Springer
Bone metastasis is considered as a considerable challenge for breast cancer patients.
Various in vitro and in vivo models have been developed to examine this occurrence. In vitro …

[HTML][HTML] An electrochemical biosensor based on β-cyclodextrin modified electrode to determine Paclitaxel as an important agent in treatment of breast cancer

C Zhang, R Lang, X Wen - Alexandria Engineering Journal, 2024 - Elsevier
Breast cancer is a severe global health issue that necessitates the development of
dependable and sensitive technology for identifying the drugs used in its treatment. The …

[HTML][HTML] Unveiling the role of ferroptosis-associated exosomal non-coding RNAs in cancer pathogenesis

Y Zhang, J Xie - Biomedicine & Pharmacotherapy, 2024 - Elsevier
The pivotal regulatory role of non-coding RNAs (ncRNAs), especially exosomal ncRNAs, in
ferroptosis significantly influences cancer cell fate. This review explores their involvement …

Transforming Albumin into a Trojan Horse of Immunotherapy-Resistant Colorectal Cancer with a High Microsatellite Instability

W Yang, Z Li, Y Li, W He, J Yan - ACS nano, 2024 - ACS Publications
The therapeutic response of microsatellite instability-high (MSI-H) colorectal cancer (CRC)
to immune checkpoint inhibitors (ICI) is indeed surprising; however, the emergence of …

Pollutants to Pathogens: The Role of Heavy Metals in Modulating TGF-β Signaling and Lung Cancer Risk

AA Bhat, E Moglad, P Bansal, H Kaur, M Deorari… - … -Research and Practice, 2024 - Elsevier
Lung cancer is a malignant tumor that develops in the lungs due to the uncontrolled growth
of aberrant cells. Heavy metals, such as arsenic, cadmium, mercury, and lead, are metallic …

Molecular docking of bioactive compounds extracted and purified from selected medicinal plant species against covid-19 proteins and in vitro evaluation

A Khanum, Y Bibi, I Khan, G Mustafa, KA Attia… - Scientific Reports, 2024 - nature.com
Bioactive compounds are secondary metabolites of plants. They offer diverse
pharmacological properties. Peganum harmala is reported to have pharmaceutical effects …