Background Radioresistance is a major factor leading to the failure of radiotherapy and poor
prognosis in tumor patients. Following the application of radiotherapy, the activity of various …

Colorectal cancer is one of the most common cancers worldwide with high mortality. Distant
metastasis and relapse are major causes of patient death. Cancer stem cells (CSCs) play a …

Like all the cells of an organism, pancreatic β-cells originate from embryonic stem cells
through a complex cellular process termed differentiation. Differentiation involves the …

Metastatic prostate carcinoma overexpresses prostate-specific membrane antigen (PSMA),
making this antigen a suitable target for radioligand therapy of the disease. Here we report …

Cancer stem cells (CSCs) have emerged as an underlying cause of cancer relapse and
resistance to treatment. Initially, biomarkers were used to identify and isolate distinct cell …

Prostate cancer (PCa) is the most diagnosed malignancy in the men worldwide. Cancer
stem cells (CSCs) are the sub-population of cells present in the tumor which possess unique …

Breast cancer is the most frequent cancer in women worldwide and late diagnosis often
adversely affects the prognosis of the disease. Radiotherapy is commonly used to treat …

Angiogenesis, the formation of new blood vessels from preexisting one, represents a critical
process for oxygen and nutrient supply to proliferating cells, therefore promoting tumor …

Radiotherapy is one of the most common treatment modalities for controlling a wide range of
tumors. However, it has been shown that radiotherapy alone is unable to completely …

Nuclear factor-κB (NF-κB) is a transcription factor regulating a wide array of genes mediating
numerous cellular processes such as proliferation, differentiation, motility and survival, to …