Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Rhenium-188 (188Re) is a high energy beta-emitting radioisotope with a short 16.9 h
physical half-life, which has been shown to be a very attractive candidate for use in …

Thyroid iodide uptake is basic to the clinical applications of radioiodine. Iodide uptake
occurs across the membrane of the thyroid follicular cells through an active transporter …

The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
active iodide transport into the thyroid gland and into several extrathyroidal tissues, in …

The 2007 Recommendations of the International Commission on Radiological Protection
(ICRP, 2007) introduced changes that affect the calculation of effective dose, and implied a …

The sodium iodide symporter (NIS) is an intrinsic plasma membrane protein that mediates
the active transport of iodide in the thyroid gland and a number of extrathyroidal tissues, in …

The iodide transporter of the thyroid (NIS) has been cloned by the group of Carrasco. The
NIS-mediated transport was studied by electrophysiological methods in NIS-expressing …

Pertechnetate (as 99mTcO4−), 123I−, and 131I− have a long and successful history of use in
the diagnosis and therapy of thyroid cancer, with uptake into thyroid tissue mediated by the …