Wound management in diabetic patient is of an extreme clinical and social concern. The
delayed and impaired healing makes it more critical for research focus. The research on …

Diabetic foot ulcers (DFUs) are a chronic, non-healing complication of diabetes that lead to
high hospital costs and, in extreme cases, to amputation. Diabetic neuropathy, peripheral …

pH and glucose dual-responsive injectable hydrogels were prepared through the cross-
linking of Schiff's base and phenylboronate ester using phenylboronic-modified chitosan …

The aggregation of amyloid-β peptide (Aβ) has been linked to the formation of neuritic
plaques, which are pathological hallmarks of Alzheimer's disease (AD). Various natural …

The human blood brain barrier (BBB) is a selective barrier formed by human brain
endothelial cells (hBECs), which is important to ensure adequate neuronal function and …

Background Diabetic foot ulcer (DFU) is a severe complication of diabetes, preceding most
diabetes-related amputations. DFUs require over US $9 billion for yearly treatment and are …

Small extracellular vesicles (SEVs) offer a promising strategy for tissue regeneration, yet
their short lifetime at the injured tissue limits their efficacy. Here, we show that kinetics of …

Hydrogels based on poly (ethylene glycol)(PEG) and derivatives have attracted significant
interest in recent years given their capacity to be well-tolerated in vivo in the context of drug …

Glioblastoma multiforme is the most lethal type of brain tumor and the established therapy
only extends patients survival to approximately one year. Its first-line treatment is based on …

Adipose-derived stem cells (ASCs) represent an important source of mesenchymal stem
cells for clinical application. During in vitro culture, ASCs quickly lose the expression of …