Xanthones and cancer: from natural sources to mechanisms of action
LC Klein‐Júnior, A Campos, R Niero… - Chemistry & …, 2020 - Wiley Online Library
Xanthones are a class of heterocyclic natural products that have been widely studied for
their pharmacological potential. In fact, they have been serving as scaffolds for the design of …
their pharmacological potential. In fact, they have been serving as scaffolds for the design of …
Recent updates on metabolite composition and medicinal benefits of mangosteen plant
Background Mangosteen (Garcinia mangostana L.) fruit has a unique sweet-sour taste and
is rich in beneficial compounds such as xanthones. Mangosteen originally been used in …
is rich in beneficial compounds such as xanthones. Mangosteen originally been used in …
Garcinone E suppresses breast cancer growth and metastasis by modulating tumor‐associated macrophages polarization via STAT6 signaling
X Nie, L Fu, Y Cheng, X Wu, K Lv, R Li… - Phytotherapy …, 2023 - Wiley Online Library
Cancer metastasis remains the most common cause of death in breast cancer patients.
Tumor‐associated macrophages (TAMs) are a novel therapeutic target for the treatment of …
Tumor‐associated macrophages (TAMs) are a novel therapeutic target for the treatment of …
New Alpha-Amylase Inhibitory Metabolites from Pericarps of Garcinia mangostana
Two new benzophenones: garcimangophenones A (6) and B (7) and five formerly reported
metabolites were purified from the pericarps EtOAc fraction of Garcinia mangostana ((GM) …
metabolites were purified from the pericarps EtOAc fraction of Garcinia mangostana ((GM) …
[HTML][HTML] Mangostanaxanthone VIIII, a new xanthone from Garcinia mangostana pericarps, α-amylase inhibitory activity, and molecular docking studies
SRM Ibrahim, GA Mohamed, MT Khayat… - Revista Brasileira de …, 2019 - SciELO Brasil
ABSTRACT A new xanthone: mangostanaxanthone VIIII [1, 3, 5, 6, 7-pentahydroxy-2-(3-
methylbut-2-enyl)-8-(3-hydroxy-3-methylbut-1-enyl) xanthone](5) and four known xanthones …
methylbut-2-enyl)-8-(3-hydroxy-3-methylbut-1-enyl) xanthone](5) and four known xanthones …
Garcixanthones B and C, new xanthones from the pericarps of Garcinia mangostana and their cytotoxic activity
Two new prenylated xanthones, garcixanthones B (1) and C (2) and six known metabolites:
gartanin (3), 1, 3, 8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl) …
gartanin (3), 1, 3, 8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl) …
The mechanisms of action of prenylated xanthones against breast, colon, and lung cancers, and their potential application against drug resistance
Cancers such as breast, colon, and lung cancers are among the leading causes of death
with alarming increases in the number of new diagnoses and mortality rates. The non …
with alarming increases in the number of new diagnoses and mortality rates. The non …
Skrining fitokimia dan profil kromatografi lapis tipis (KLT) tumbuhan antimalaria asal Indonesia
M Arifuddin, M Bone - Jurnal Sains dan Kesehatan, 2020 - jsk.ff.unmul.ac.id
Telah dilakukan pengujian skrining fitokimia dengan tujuan mendeteksi senyawa metabolit
sekunder pada beberapa tumbuhan, yakni batang Brotowali (Tinospora crispa), daun …
sekunder pada beberapa tumbuhan, yakni batang Brotowali (Tinospora crispa), daun …
α‐Amylase inhibition of xanthones from Garcinia mangostana pericarps and their possible use for the treatment of diabetes with molecular docking studies
SRM Ibrahim, GA Mohamed… - Journal of food …, 2019 - Wiley Online Library
Chromatographic separation of the methanol extract of Garcinia mangostana (mangosteen,
Guttiferae) dried pericarps led to the isolation and structural characterization of a new …
Guttiferae) dried pericarps led to the isolation and structural characterization of a new …
Mangostanaxanthone VIII, a new xanthone from Garcinia mangostana and its cytotoxic activity
SRM Ibrahim, HM Abdallah… - Natural product …, 2019 - Taylor & Francis
A new prenylated xanthone, mangostanaxanthone VIII (7) and six known metabolites:
gartanin (1), 1, 3, 8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl) …
gartanin (1), 1, 3, 8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl) …