Mesenchymal stem cell-derived extracellular vesicles for therapeutic use and in bioengineering applications

C McLaughlin, P Datta, YP Singh, A Lo, S Horchler… - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are small lipid bilayer-delimited particles that are naturally
released from cells into body fluids, and therefore can travel and convey regulatory functions …

Exosomic microRNAs in the tumor microenvironment

P Neviani, M Fabbri - Frontiers in medicine, 2015 - frontiersin.org
Dissecting the crosstalk between tumor cells and tumor microenvironment is quickly
becoming the new frontier in cancer research. It is now widely accepted that cancer cells can …

Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation

X Wang, O Omar, F Vazirisani, P Thomsen, K Ekström - PloS one, 2018 - journals.plos.org
Human mesenchymal stem cell (hMSC)-derived exosomes have shown regenerative
effects, but their role in osteogenesis and the underlying mechanism are yet to be …

Mesenchymal stem/stromal cell function in modulating cell death

A Naji, B Favier, F Deschaseaux… - Stem cell research & …, 2019 - Springer
Mesenchymal stem/stromal cells (MSCs) delivered as cell therapy to individuals with
degenerative and/or inflammatory disorders can help improve organ features and resolve …

[HTML][HTML] High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular …

AM Larey, TM Spoerer, KR Daga, MG Morfin… - Bioactive Materials, 2024 - Elsevier
Due to their immunomodulatory function, mesenchymal stromal cells (MSCs) are a
promising therapeutic with the potential to treat neuroinflammation associated with …

[HTML][HTML] Stromal cell extracellular vesicular cargo mediated regulation of breast cancer cell metastasis via ubiquitin conjugating enzyme E2 N pathway

KC Vallabhaneni, P Penfornis, F Xing, Y Hassler… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (hMSCs) have been used to understand the stromal cell
properties in solid tumors because of their ablity to differentiate into most cell types. We …

Regenerative potential of mesenchymal stem cell-derived extracellular vesicles

DS Thalakiriyawa, PR Jayasooriya… - Current molecular …, 2022 - ingentaconnect.com
Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into diverse cell
lineages. MSC based therapy has become a widely experimented treatment strategy in …

Optimising Extracellular Vesicle Metabolomic Methodology for Prostate Cancer Biomarker Discovery

MA Hamed, V Wasinger, Q Wang, J Biazik, P Graham… - Metabolites, 2024 - mdpi.com
Conventional diagnostic tools for prostate cancer (PCa), such as prostate-specific antigen
(PSA), transrectal ultrasound (TRUS), digital rectal examination (DRE), and tissue biopsy …

Crosstalk between Exosomes and CAFs During Tumorigenesis, Exosomederived Biomarkers, and Exosome-mediated Drug Delivery

X Li, X Wu, X Su - Letters in Drug Design & Discovery, 2023 - ingentaconnect.com
Cancer-Associated Fibroblasts (CAFs) originate from the activation of fibroblasts in the
Tumor Microenvironment (TME) during tumorigenesis, resulting in the promotion of tumor …