Epidemiology and molecular biology of HPV variants in cervical cancer: the state of the art in Mexico

JO Muñoz-Bello, A Carrillo-García… - International Journal of …, 2022 - mdpi.com
Cervical cancer (CC) continues to be a major public health problem in Mexico, ranking
second among cancers in women. A persistent infection with human papillomaviruses (HPV) …

HPV-associated oropharyngeal cancer: In search of surrogate biomarkers for early lesions

YX Lim, NJ D'Silva - Oncogene, 2024 - nature.com
The incidence of oropharyngeal cancer (OPSCC) has escalated in the past few decades;
this has largely been triggered by high-risk human papillomavirus (HPV). Early cancer …

HPV is a cargo for the COPI sorting complex during virus entry

MC Harwood, TT Woo, Y Takeo, D DiMaio, B Tsai - Science Advances, 2023 - science.org
During entry, human papillomavirus (HPV) traffics from the cell surface to the endosome and
then to the trans-Golgi network (TGN) and Golgi apparatus. HPV must transit across the …

Cell-penetrating peptide mediates intracellular membrane passage of human papillomavirus L2 protein to trigger retrograde trafficking

P Zhang, GM da Silva, C Deatherage, C Burd… - Cell, 2018 - cell.com
Cell-penetrating peptides (CPPs) are short protein segments that can transport cargos into
cells. Although CPPs are widely studied as potential drug delivery tools, their role in normal …

Retromer stabilizes transient membrane insertion of L2 capsid protein during retrograde entry of human papillomavirus

J Xie, P Zhang, M Crite, CV Lindsay, D DiMaio - Science Advances, 2021 - science.org
Retromer, a cellular protein trafficking complex, sorts human papillomaviruses (HPVs) into
the retrograde pathway for transport of HPV to the nucleus during virus entry. Here, we …

[HTML][HTML] The long and winding road: human papillomavirus entry and subcellular trafficking

MA Ozbun, SK Campos - Current opinion in virology, 2021 - Elsevier
Human papillomaviruses (HPVs) infect and replicate in differentiating mucosal and
cutaneous epithelium. Most HPV infections are asymptomatic or cause transient benign …

Elevated A-to-I RNA editing in COVID-19 infected individuals

R Merdler-Rabinowicz, D Gorelik, J Park… - NAR Genomics and …, 2023 - academic.oup.com
Given the current status of coronavirus disease 2019 (COVID-19) as a global pandemic, it is
of high priority to gain a deeper understanding of the disease's development and how the …

Vesicular trafficking permits evasion of cGAS/STING surveillance during initial human papillomavirus infection

BL Uhlorn, R Jackson, S Li, SM Bratton… - PLoS …, 2020 - journals.plos.org
Oncogenic human papillomaviruses (HPVs) replicate in differentiating epithelium, causing
5% of cancers worldwide. Like most other DNA viruses, HPV infection initiates after …

Engineering proteins for cell entry

X Feng, R Chang, H Zhu, Y Yang, Y Ji… - Molecular …, 2023 - ACS Publications
Proteins are essential for life, as they participate in all vital processes in the body. In the past
decade, delivery of active proteins to specific cells and organs has attracted increasing …

Non-enveloped virus membrane penetration: New advances leading to new insights

ML Pletan, B Tsai - PLoS Pathogens, 2022 - journals.plos.org
Host cell membranes pose a particular challenge for non-enveloped viruses. Whereas
enveloped viruses enter cells by fusing their lipid envelopes with the cellular membrane …