[HTML][HTML] The role of IGRA in the diagnosis of tuberculosis infection, differentiating from active tuberculosis, and decision making for initiating treatment or preventive …

D Goletti, G Delogu, A Matteelli, GB Migliori - International Journal of …, 2022 - Elsevier
ABSTRACT Objectives The World Health Organization estimated that a quarter of the global
population is infected by Mycobacterium tuberculosis (Mtb). A better control of tuberculosis …

Mycobacterial infections in adults with haematological malignancies and haematopoietic stem cell transplants: guidelines from the 8th European Conference on …

A Bergeron, M Mikulska, J De Greef… - The Lancet Infectious …, 2022 - thelancet.com
Mycobacterial infections, both tuberculosis and nontuberculous, are more common in
patients with haematological malignancies and haematopoietic stem cell transplant …

Clinical standards for the diagnosis, treatment and prevention of TB infection

GB Migliori, SJ Wu, A Matteelli, D Zenner… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND: Tuberculosis (TB) preventive therapy (TPT) decreases the risk of
developing TB disease and its associated morbidity and mortality. The aim of these clinical …

Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights

M Coleman, L Martinez, G Theron, R Wood, B Marais - Pathogens, 2022 - mdpi.com
Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …

The ubiquitin ligase TRIM32 promotes the autophagic response to Mycobacterium tuberculosis infection in macrophages

A Romagnoli, M Di Rienzo, E Petruccioli, C Fusco… - Cell Death & …, 2023 - nature.com
Mycobacterium tuberculosis (Mtb) is known to evade host immune responses and persist in
macrophages for long periods. A mechanism that the host uses to combat Mtb is xenophagy …

Disease transmission by patients with subclinical tuberculosis

HV Nguyen, E Tiemersma, NV Nguyen… - Clinical Infectious …, 2023 - academic.oup.com
Background Subclinical tuberculosis has been increasingly recognized as a separate state
in the spectrum of the disease. However, evidence on the transmissibility of subclinical …

Making cough count in tuberculosis care

AJ Zimmer, C Ugarte-Gil, R Pathri, P Dewan… - Communications …, 2022 - nature.com
Cough assessment is central to the clinical management of respiratory diseases, including
tuberculosis (TB), but strategies to objectively and unobtrusively measure cough are lacking …

Research tests for the diagnosis of tuberculosis infection

T Alonzi, F Repele, D Goletti - Expert Review of Molecular …, 2023 - Taylor & Francis
Introduction Despite huge efforts, tuberculosis (TB) is still a major public health threat
worldwide, it is estimated that a quarter of the global population is infected by …

Management of tuberculosis infection: current situation, recent developments and operational challenges

G Agbota, M Bonnet, C Lienhardt - Pathogens, 2023 - mdpi.com
Tuberculosis infection (TBI) is defined as a state of infection in which individuals host live
Mycobacterium tuberculosis with or without clinical signs of active TB. It is now understood …

From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning

LS Li, L Yang, L Zhuang, ZY Ye, WG Zhao… - Military Medical …, 2023 - Springer
Latent tuberculosis infection (LTBI) has become a major source of active tuberculosis (ATB).
Although the tuberculin skin test and interferon-gamma release assay can be used to …