The impact of genetics on physiology and sports performance is one of the most debated
research aspects in sports sciences. Nearly 200 genetic polymorphisms have been found to …

Clinical genetics has an important role in the healthcare system to provide a definitive
diagnosis for many rare syndromes. It also can have an influence over genetics prevention …

Cancers develop due to the accumulation of genetic and epigenetic alterations. Genetic
alterations are induced by aging, mutagenic chemicals, ultraviolet light, and other factors; …

Over the past decade, genomic analyses of single cells—the fundamental units of life—have
become possible. Single-cell DNA sequencing has shed light on biological questions that …

Cellular DNA is constantly chemically altered by exogenous and endogenous agents. As all
processes of life depend on the transmission of the genetic information, multiple biological …

Abstract Error-corrected Next Generation Sequencing (ecNGS) is rapidly emerging as a
valuable, highly sensitive and accurate method for detecting and characterizing mutations in …

This review focuses on DNA damage caused by a variety of oxidizing, alkylating, and
nitrating species, and it may play an important role in the pathophysiology of inflammation …

Mitochondrial and plastid genomes in land plants exhibit some of the slowest rates of
sequence evolution observed in any eukaryotic genome, suggesting an exceptional ability …

Detection of cancer-associated somatic mutations has broad applications for oncology and
precision medicine. However, this becomes challenging when cancer-derived DNA is in low …

The last decade witnessed extraordinary advances in “omics” methods, particularly
transcriptomics, proteomics and metabolomics, enabling toxicologists to integrate …