Vascular regeneration is a challenging topic in tissue repair. As one of the important
components of the neurovascular unit (NVU), pericytes play an essential role in the …

Pericytes are a heterogeneous population of mesenchymal cells located on the abluminal
surface of microvessels, where they provide structural and biochemical support. Pericytes …

Single-cell RNA sequencing (scRNA-seq) enables specific profiling of cell populations at
single-cell resolution. The osteoimmunology microenvironment in the occurrence and …

A comprehensive understanding of the cellular heterogeneity and molecular mechanisms
underlying the development, homeostasis, and disease of human intervertebral disks (IVDs) …

Bone regeneration following injury is initiated by inflammatory signals and occurs in
association with infiltration by sensory nerve fibers. Together, these events are believed to …

Stromal progenitors are found in many different tissues, where they play an important role in
the maintenance of tissue homeostasis owing to their ability to differentiate into parenchymal …

The vascular wall is comprised of distinct layers controlling angiogenesis, blood flow, vessel
anchorage within organs, and cell and molecule transit between blood and tissues …

Innate mesenchymal stem cells exhibiting multilineage differentiation and tissue (re)
generative—or pathogenic—properties reside in perivascular niches. Subsets of these …

For the survival and integration of complex large-sized tissue-engineered (TE) organ
constructs that exceed the maximal nutrients and oxygen diffusion distance required for cell …

WHIM Syndrome is a rare immunodeficiency caused by gain-of-function CXCR4 mutations.
Here we report a decrease in bone mineral density in 25% of WHIM patients and bone …