With computation models playing an ever increasing role in the advancement of science, it is
important that researchers understand what it means to model something; recognize the …

A complex network of transcription factor interactions propagates across the larval eye disc
to establish columns of evenly-spaced R8 precursor cells, the founding cells of Drosophila …

The architecture and morphogenetic properties of tissues are founded in the tissue-specific
regulation of cell behaviors. In endochondral bones, the growth plate cartilage promotes …

We highlight recent progress in understanding cadherin and integrin function in the model
organism Drosophila. New functions for these adhesion receptors continue to be discovered …

Epithelial cells connect via cell-cell junctions to form sheets of cells with separate cellular
compartments. These cellular connections are essential for the generation of cellular forms …

The regular hexagonal array morphology of facets (ommatidia) in the Drosophila compound
eye is accomplished by regulation of cell differentiation and planar cell polarity during …

The folding of epithelial sheets, accompanied by cell shape changes and rearrangements,
gives rise to three-dimensional structures during development. Recently, some aspects of …

In a confluent, single-cell tissue layer, we show that cell shapes and statistics correlate
directly with the tissue's mechanical properties, described by an energy functional with …

Cell–cell adhesion is at the center of structure and dynamics of epithelial tissue. E-cadherin–
catenin complexes mediate Ca2+-dependent trans-homodimerization and constitute the …

Epithelial tissues form and repair in complex processes influenced by molecular and
physical factors. Recent years have witnessed the development of new microscopy …