Brain glucose metabolism: integration of energetics with function

GA Dienel - Physiological reviews, 2019 - journals.physiology.org
Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …

[HTML][HTML] Kinetic modeling and parametric imaging with dynamic PET for oncological applications: general considerations, current clinical applications, and future …

A Dimitrakopoulou-Strauss, L Pan… - European journal of …, 2021 - Springer
Dynamic PET (dPET) studies have been used until now primarily within research purposes.
Although it is generally accepted that the information provided by dPET is superior to that of …

Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder

LR Baxter, JM Schwartz, KS Bergman… - Archives of general …, 1992 - jamanetwork.com
• We used positron emission tomography to investigate local cerebral metabolic rates for
glucose (LCMRG1c) in patients with obsessive-compulsive disorder before and after …

Practice-related changes in human brain functional anatomy during nonmotor learning

ME Raichle, JA Fiez, TO Videen, AMK MacLeod… - Cerebral …, 1994 - academic.oup.com
Practice of a novel task leads to improved performance. The brain mechanisms associated
with practice-induced improvement in performance are largely unknown. To address this …

Tumor treatment response based on visual and quantitative changes in global tumor glycolysis using PET-FDG imaging: the visual response score and the change in …

SM Larson, Y Erdi, T Akhurst, M Mazumdar… - Clinical Positron …, 1999 - Elsevier
“Functional” tumor treatment response parameters have been developed to measure
treatment induced biochemical changes in the entire tumor mass, using positron emission …

Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder

LL Howell, KA Cunningham - Pharmacological reviews, 2015 - ASPET
Cocaine exhibits prominent abuse liability, and chronic abuse can result in cocaine use
disorder with significant morbidity. Major advances have been made in delineating …

FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease

L Mosconi, R Mistur, R Switalski, WH Tsui… - European journal of …, 2009 - Springer
Purpose We report the first clinicopathological series of longitudinal FDG-PET scans in post-
mortem (PM) verified cognitively normal elderly (NL) followed to the onset of Alzheimer's …

Prediction of cognitive decline in normal elderly subjects with 2-[18F]fluoro-2-deoxy-d-glucose/positron-emission tomography (FDG/PET)

MJ De Leon, A Convit, OT Wolf… - Proceedings of the …, 2001 - National Acad Sciences
Neuropathology studies show that patients with mild cognitive impairment (MCI) and
Alzheimer's disease typically have lesions of the entorhinal cortex (EC), hippocampus (Hip) …

Hippocampal formation glucose metabolism and volume losses in MCI and AD

S De Santi, MJ de Leon, H Rusinek, A Convit… - Neurobiology of …, 2001 - Elsevier
We used MRI volume sampling with coregistered and atrophy corrected FDG-PET scans to
test three hypotheses: 1) hippocampal formation measures are superior to temporal …

Inverse association between BMI and prefrontal metabolic activity in healthy adults

ND Volkow, GJ Wang, F Telang, JS Fowler… - …, 2009 - Wiley Online Library
Obesity has been associated with a higher risk for impaired cognitive function, which most
likely reflects associated medical complications (ie, cerebrovascular pathology). However …