The role of betaine in the liver and kidney has been well documented, even from the cellular
and molecular point of view. Despite literature reporting positive effects of betaine …

Abstract Purpose of Review This review summarizes neurotransmitter, peptide, and other
neurohormone abnormalities associated with posttraumatic stress disorder (PTSD) and …

There is a need to identify new and more effective treatments for posttraumatic stress
disorder (PTSD). Allopregnanolone and its stereoisomer pregnanolone (together termed …

Ubiquitous expression of GABA type A receptors (GABAAR) in the central nervous system
establishes their central role in coordinating most aspects of neural function and …

Post-traumatic stress disorder (PTSD) is a stress-associated complex and debilitating
psychiatric disorder due to an imbalance of neurotransmitters in response to traumatic …

In the healthy brain, gamma-aminobutyric acid (GABA) is regulated by neurons and glia.
This begs the question: what happens in the malfunctioning brain? There are many reasons …

Objective There is a major unmet need for a molecular biomarker of seizures or epilepsy that
lends itself to fast, affordable detection in an easy‐to‐use point‐of‐care device. Purines such …

Background The major sites for fast synaptic inhibition in the central nervous system (CNS)
are ion channels activated by γ-aminobutyric acid (GABA). These receptors are referred as …

Recent progress in the field of neurobiology supported by clinical evidence gradually
reveals the mystery of human brain functioning. So far, many psychiatric disorders have …

A stressor-related disorder wherein traumatic experience precipitates protracted disruptions
to mood and cognition, post-traumatic stress disorder (PTSD) is associated with wide …