HTLV-1-associated myelopathy/tropical spastic paraparesis

CRM Bangham, A Araujo, Y Yamano… - Nature reviews Disease …, 2015 - nature.com
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the …

HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

Cytokine networks dysregulation during HTLV-1 infection and associated diseases

N Futsch, G Prates, R Mahieux, J Casseb, H Dutartre - Viruses, 2018 - mdpi.com
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a neural chronic
inflammation, called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …

Viral source-independent high susceptibility of dendritic cells to human T-cell leukemia virus type 1 infection compared to that of T lymphocytes

S Alais, R Mahieux, H Dutartre - Journal of virology, 2015 - Am Soc Microbiol
MATERIALS AND METHODS Cells. Jurkat, Jurkat-LTR-Luc (17), and HTLV-1-infected T-cell
lines (MT-2 or C91PL) and activated primary blood lymphocytes (PBLs; referred to …

Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL

M Kannagi, A Hasegawa, Y Nagano, S Kimpara… - Retrovirology, 2019 - Springer
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL),
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other …

HTLV-1 infection of myeloid cells: from transmission to immune alterations

B Rocamonde, A Carcone, R Mahieux, H Dutartre - Retrovirology, 2019 - Springer
Human T cell leukemia virus type 1 (HTLV-1), the etiological agent of adult T-cell
leukemia/lymphoma (ATLL) and the demyelinating neuroinflammatory disease known as …

HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity

J Wang, S Yang, L Liu, H Wang, B Yang - Virus research, 2017 - Elsevier
The cellular antiviral innate immune system is essential for host defense and viruses have
evolved a variety of strategies to evade the innate immunity. Human T lymphotropic virus …

[HTML][HTML] Molecular targeting for treatment of human T-lymphotropic virus type 1 infection

A Soltani, SI Hashemy, FZ Avval, A Soleimani… - Biomedicine & …, 2019 - Elsevier
Human T-cell lymphotropic virus type 1 (HTLV-1) infection is linked to adult T-cell leukemia-
lymphoma (ATLL) and HTLV-I-associated myelopathy/tropical spastic paraparesis …

Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells

G Rizkallah, S Alais, N Futsch, Y Tanaka… - PLOS …, 2017 - journals.plos.org
Human T lymphotropic Virus type 1 (HTLV-1) is the etiological agent of Adult T cell
Leukemia/Lymphoma (ATLL) and HTLV-1-Associated Myelopathy/Tropical Spastic …

Sensing of cell-associated HTLV by plasmacytoid dendritic cells is regulated by dense β-galactoside glycosylation

S Assil, N Futsch, E Décembre, S Alais… - PLoS …, 2019 - journals.plos.org
Human T Lymphotropic virus (HTLV) infection can persist in individuals resulting, at least in
part, from viral escape of the innate immunity, including inhibition of type I interferon …