Systems metabolic engineering of microorganisms for food and cosmetics production

KR Choi, SY Lee - Nature Reviews Bioengineering, 2023 - nature.com
The demand for sustainable and environmentally friendly sources of foods and cosmetics is
increasing owing to concerns about the rapid growth of the global population and climate …

Genome-scale metabolic modeling enables in-depth understanding of big data

A Passi, JD Tibocha-Bonilla, M Kumar, D Tec-Campos… - Metabolites, 2021 - mdpi.com
Genome-scale metabolic models (GEMs) enable the mathematical simulation of the
metabolism of archaea, bacteria, and eukaryotic organisms. GEMs quantitatively define a …

Scripting a new dialogue between diazotrophs and crops

S Chakraborty, M Venkataraman, V Infante… - Trends in …, 2024 - cell.com
Diazotrophs are bacteria and archaea that can reduce atmospheric dinitrogen (N 2) into
ammonium. Plant–diazotroph interactions have been explored for over a century as a …

Efficient plasmid transfer via natural competence in a microbial co‐culture

YY Cheng, Z Zhou, JM Papadopoulos… - Molecular Systems …, 2023 - embopress.org
The molecular and ecological factors shaping horizontal gene transfer (HGT) via natural
transformation in microbial communities are largely unknown, which is critical for …

Mercury bioremediation in aquatic environment by genetically modified bacteria with self-controlled biosecurity circuit

Y Xue, P Du, AAI Shendi, B Yu - Journal of Cleaner Production, 2022 - Elsevier
Heavy metal pollution such as mercury (Hg 2+) poses a severe threat to food security
worldwide because of enrichment through food chain and, eventually, to the human body …

Microbial engineering strategies to utilize waste feedstock for sustainable bioproduction

N Aggarwal, HL Pham, B Ranjan, M Saini… - Nature Reviews …, 2024 - nature.com
The desire to move from a fossil fuel-based 'take–make–dispose'economy to a bio-based
circular economy has generated great interest in microbial metabolic engineering for its …

Advances in engineering genetic circuits for microbial biocontainment

Y Ma, A Manna, TS Moon - Current Opinion in Systems Biology, 2023 - Elsevier
The development of synthetic biology has resulted in the use of genetically engineered
microbes (GEMs), becoming increasingly critical for addressing global issues such as …

Biocontainment of genetically engineered algae

J Sebesta, W Xiong, MT Guarnieri, J Yu - Frontiers in plant science, 2022 - frontiersin.org
Algae (including eukaryotic microalgae and cyanobacteria) have been genetically
engineered to convert light and carbon dioxide to many industrially and commercially …

Eliminating host-guest incompatibility via enzyme mining enables the high-temperature production of N-acetylglucosamine

Y Wu, J Liu, X Han, X Meng, M Li, J Wang, H Xue… - Iscience, 2023 - cell.com
The host-guest incompatibility between a production host and non-native enzymes has
posed an arduous challenge for synthetic biology, particularly between mesophile-derived …

Current advances of biocontainment strategy in synthetic biology

X Zhu, Z Zhang, B Jia, Y Yuan - Chinese Journal of Chemical Engineering, 2023 - Elsevier
Synthetic biotechnology has led to the widespread application of genetically modified
organisms (GMOs) in biochemistry, bioenergy, and therapy. However, the uncontrolled …