The bacterial replication initiator DnaA. DnaA and oriC, the bacterial mode to initiate DNA replication
W Messer - FEMS microbiology reviews, 2002 - academic.oup.com
The initiation of replication is the central event in the bacterial cell cycle. Cells control the
rate of DNA synthesis by modulating the frequency with which new chains are initiated, like …
rate of DNA synthesis by modulating the frequency with which new chains are initiated, like …
Bacteriophage replication modules
C Weigel, H Seitz - FEMS microbiology reviews, 2006 - academic.oup.com
Bacteriophages (prokaryotic viruses) are favourite model systems to study DNA replication
in prokaryotes, and provide examples for every theoretically possible replication …
in prokaryotes, and provide examples for every theoretically possible replication …
The interaction domains of the DnaA and DnaB replication proteins of Escherichia coli
H Seitz, C Weigel, W Messer - Molecular microbiology, 2000 - Wiley Online Library
The initiation of chromosome replication in Escherichia coli requires the recruitment of the
replicative helicase DnaB from the DnaBC complex to the unwound region within the …
replicative helicase DnaB from the DnaBC complex to the unwound region within the …
Nucleotide and partner-protein control of bacterial replicative helicase structure and function
MS Strycharska, E Arias-Palomo, AY Lyubimov… - Molecular cell, 2013 - cell.com
Cellular replication forks are powered by ring-shaped, hexameric helicases that encircle and
unwind DNA. To better understand the molecular mechanisms and control of these …
unwind DNA. To better understand the molecular mechanisms and control of these …
Myricetin inhibits Escherichia coli DnaB helicase but not primase
Primase and DnaB helicase play central roles during DNA replication initiation and
elongation. Both enzymes are drug targets because they are essential, persistent among …
elongation. Both enzymes are drug targets because they are essential, persistent among …
Regulation of bacterial priming and daughter strand synthesis through helicase-primase interactions
JE Corn, JM Berger - Nucleic acids research, 2006 - academic.oup.com
The replisome is a multi-component molecular machine responsible for rapidly and
accurately copying the genome of an organism. A central member of the bacterial replisome …
accurately copying the genome of an organism. A central member of the bacterial replisome …
Coumarin-based inhibitors of Bacillus anthracis and Staphylococcus aureus replicative DNA helicase: chemical optimization, biological evaluation, and antibacterial …
B Li, R Pai, M Di, D Aiello, MH Barnes… - Journal of medicinal …, 2012 - ACS Publications
The increasing prevalence of drug-resistant bacterial infections demands the development
of new antibacterials that are not subject to existing mechanisms of resistance. Previously …
of new antibacterials that are not subject to existing mechanisms of resistance. Previously …
Mechanism and stoichiometry of interaction of DnaG primase with DnaB helicase of Escherichia coli in RNA primer synthesis
AV Mitkova, SM Khopde, SB Biswas - Journal of Biological Chemistry, 2003 - ASBMB
Initiation and synthesis of RNA primers in the lagging strand of the replication fork in
Escherichia coli requires the replicative DnaB helicase and the DNA primase, the DnaG …
Escherichia coli requires the replicative DnaB helicase and the DNA primase, the DnaG …
The Caulobacter crescentus DciA promotes chromosome replication through topological loading of the DnaB replicative helicase at replication forks
S Ozaki, D Wang, Y Wakasugi, N Itani… - Nucleic acids …, 2022 - academic.oup.com
The replicative DNA helicase translocates on single-stranded DNA to drive replication forks
during chromosome replication. In most bacteria the ubiquitous replicative helicase, DnaB …
during chromosome replication. In most bacteria the ubiquitous replicative helicase, DnaB …
The crystal structure of a replicative hexameric helicase DnaC and its complex with single-stranded DNA
YH Lo, KL Tsai, YJ Sun, WT Chen… - Nucleic Acids …, 2009 - academic.oup.com
DNA helicases are motor proteins that play essential roles in DNA replication, repair and
recombination. In the replicative hexameric helicase, the fundamental reaction is the …
recombination. In the replicative hexameric helicase, the fundamental reaction is the …