Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors

B Sever, C Türkeş, MD Altıntop, Y Demir… - International Journal of …, 2020 - Elsevier
Alzheimer's disease (AD) is a complex, predominant, and progressive form of dementia. The
treatment of AD alters depending on the cognitive and behavioral symptoms. The utility of …

Exploring the interaction between 1, 4-butanediol and acid phosphatase using spectroscopic techniques and molecular modeling studies

S Moradi, B Shareghi, AA Saboury, S Farhadian… - Journal of Molecular …, 2023 - Elsevier
The functional characteristics of enzymes greatly rely on their stability, which is a vital factor
to be considered when utilizing these biomolecules in industrial settings. This study …

Investigation on the interaction of acid phosphatase with putrescine using docking, simulations methods and multispectroscopic techniques

S Moradi, B Shareghi, AA Saboury… - International journal of …, 2020 - Elsevier
The effect of putrescine on the dynamics, conformation, and kinetics of acid phosphatase
investigated via different experimental and theoretical methods. The Stern-Volmer constants …

Synthesis of 3-oxadiazole-substituted imidazo [1, 2-a] pyridines by nickel immobilized on multifunctional amphiphilic porous polysulfonamide–melamine

S Alavinia, R Ghorbani-Vaghei - New Journal of Chemistry, 2020 - pubs.rsc.org
Due to the fact that developing sustainable processes and applying eco-friendly
heterogeneous catalysts have become widely significant, researchers have paid great …

Spectroscopy and molecular dynamic study of the interaction of calf thymus DNA by anticancer Pt complex with butyl glycine ligand

KT Hafshajani, N Sohrabi, ME Moghadam… - Spectrochimica Acta Part …, 2023 - Elsevier
Despite the past few decades since the discovery of anticancer drugs, there is still no
definitive treatment for its treatment. Cisplatin is a chemotherapy medication used to treat …

New platinum (II) complexes based on Schiff bases: Synthesis, specification, X-ray structure, ADMET, DFT, molecular docking, and anticancer activity against breast …

M Eslami Moghadam, M Hasanzadeh Esfahani… - JBIC Journal of …, 2023 - Springer
Acylpyrazolone-based Schiff base ligands (HL n) and their corresponding Pt (II) complexes
with the general formula [Pt (L n)(Cl)](n= 1–3) were synthesized and characterized by …

The concept of protein folding/unfolding and its impacts on human health

L Alaei, M Ashengroph… - Advances in protein …, 2021 - Elsevier
Proteins have evolved in specific 3D structures and play different functions in cells and
determine various reactions and pathways. The newly synthesized amino acid chains once …

The influence of Cadaverine on the structure, stability, and activity of acid phosphatase

S Moradi, B Shareghi, AA Saboury… - Journal of Molecular …, 2022 - Elsevier
This research aimed to study the interaction between cadaverine and acid phosphatase.
Therefore, the structural alterations of acid phosphatases that were caused by Cadaverine …

A new series of sulfa drugs containing pyrazolyl acylthiourea moiety: Synthesis, experimental and theoretical spectral characterization and molecular docking studies

İ Koca, S Yiğitcan, M Gümüş, H Gökce, Y Sert - Journal of Molecular …, 2020 - Elsevier
Ten new molecules of sulfa drugs including pyrazolyl acylthiourea groups (3a-3j) were
synthesized and characterized with the help of elemental analysis, HRMS, FT-IR, 1 H NMR …

Novel benzenesulfonamides containing dual triazole moiety with selective carbonic anhydrase inhibition and anticancer activity

A Buza, C Türkeş, M Arslan, Y Demir, B Dincer… - RSC Medicinal …, 2024 - pubs.rsc.org
A series of sulfonamides incorporating a 1, 2, 3-triazolyloxime substituted 1, 2, 3-triazolyl
moiety was conceptualized and synthesized as human carbonic anhydrase (hCA) inhibitors …