Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

Considered as the “King of spices”, black pepper (Piper nigrum L.) is a widely used spice
which adds flavor of its own to dishes, and also enhances the taste of other ingredients …

Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …

Oxidative stress is usually associated with many neurodegenerative diseases. In this study,
the gas chromatography–mass spectrometry (GC–MS) analysis of cold-pressed oil (CPO) …

Background The worldwide corona virus disease outbreak, generally known as COVID-19
pandemic outbreak resulted in a major health crisis globally. The morbidity and transmission …

Ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE) of the Thai
herbal formula Kleeb Bua Daeng (KBD) were optimized separately and compared. A Box …

Piper nigrum Linnaeus is often used as a treatment for chills, stomach diseases, and other
ailments. Piperine has many biological functions; however, its mechanism for preventing …

Piper nigrum L. is commonly used worldwide and its pericarp, stalks, leaves will be major
wastes materials. 42 amide alkaloids were identified in black, white pepper and pericarp by …

The gut-microbiota–brain axis plays an important role in stress-related disorders, and
dysfunction of this complex bidirectional system is associated with Alzheimer's disease. This …

Piperine, an important natural product, has a good anti-inflammatory effect. However, few
researchers have studied its mechanism in these pathways. The objective of this research …