Development of human serum albumin fluorescent probes in detection, imaging, and disease therapy

Y Wang, F Huo, C Yin - The Journal of Physical Chemistry B, 2024 - ACS Publications
Human serum albumin (HSA) acts as a repository and transporter of substances in the
blood. An abnormal concentration may indicate the occurrence of liver-and kidney-related …

Excited-state intramolecular proton transfer (ESIPT)-based fluorescent probes for biomarker detection: design, mechanism, and application

H Gu, W Wang, W Wu, M Wang, Y Liu, Y Jiao… - Chemical …, 2023 - pubs.rsc.org
Biomarkers are essential in biology, physiology, and pharmacology; thus, their detection is
of extensive importance. Fluorescent probes provide effective tools for detecting biomarkers …

Aggregation and binding-directed FRET modulation of conjugated polymer materials for selective and point-of-care monitoring of serum albumins

S Hussain, X Chen, C Wang, Y Hao, X Tian… - Analytical …, 2022 - ACS Publications
Nonspecific interactions of conjugated polymers (CPs) with various proteins prove to be a
major impediment for researchers when designing a suitable CP-based probe for the …

Smartphone-based on-site detection of hydrogen peroxide in milk by using a portable ratiometric fluorescent probe

Z Xu, C Zeng, Y Zhao, M Zhou, T Lv, C Song, T Qin… - Food Chemistry, 2023 - Elsevier
The on-site detection of hydrogen peroxide (H 2 O 2) is important for maintaining food safety
as the ingestion of H 2 O 2 can lead to serious pathological conditions. However, most …

General Method for Pesticide Recognition Using Albumin-Based Host–Guest Ensembles

T Qin, X Zhao, T Lv, G Yao, Z Xu, L Wang, C Zhao… - ACS …, 2022 - ACS Publications
The massive use of pesticides nowadays has led to serious consequences for the
environment and public health. Fluorescence analytical methods for pesticides are …

Dual-channel recognition of human serum albumin and glutathione by fluorescent probes with site-dependent responsive features

D Yuan, K Pan, S Xu, L Wang - Analytical Chemistry, 2022 - ACS Publications
Design of chemical probes with high specificity and responses are particularly intriguing. In
this work, a fluorescent probe (M–OH–SO 3) with dual-channel spectral responses toward …

Detection of Urinary Albumin Using a “Turn‐on” Fluorescent Probe with Aggregation‐Induced Emission Characteristics

Q Hu, B Yao, TC Owyong, S Prashanth… - Chemistry–An Asian …, 2021 - Wiley Online Library
Human serum albumin (HSA) is a broadly used biomarker for the diagnosis of various
diseases such as chronic kidney disease. Here, a fluorescent probe TC426 with aggregation …

Engineering a selective fluorescent sensor with a high signal-to-background ratio for microalbumin detection and imaging

L Su, F Yang, W Li, H Li, C Wang, Q Wang… - Materials Chemistry …, 2022 - pubs.rsc.org
Abnormal concentrations of human serum albumin (HSA) are closely related to the
occurrence of various diseases, such as liver cirrhosis and kidney disease. Thus, it is of …

A novel protein-based supramolecular recognition approach for ratiometric fluorescence detection of fipronil

T Qin, X Zhao, T Jia, X Du, T Lv, Y Tian, Z Zhang… - Sensors and Actuators B …, 2022 - Elsevier
Fipronil, a wildly used pesticide, exhibits high toxicity to pollinators, aquatic organisms,
farmland birds, as well as mammals that have GABA receptors, including humans. Thus …

Fluorescence discrimination of HSA from BSA: A close look at the albumin-induced restricted intramolecular rotation of flavonoid probe

B Liu, T Lv, X Zhao, M Zhou, C Song, C Zeng… - … Acta Part A: Molecular …, 2022 - Elsevier
Discrimination of human serum albumin (HSA) from bovine serum albumin (BSA) based on
the fluorescence probe technique is still challenging due to similar chemical structures. In …