Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …

Since 2016, Yemen has been experiencing the largest cholera outbreak in modern history.
Multidrug resistance (MDR) emerged among Vibrio cholerae isolates from cholera patients …

The ability of antimicrobial resistance (AR) to transfer, on mobile genetic elements (MGEs)
between bacteria, can cause the rapid establishment of multidrug resistance (MDR) in …

Salmonella enterica is a common foodborne illness in the United States and globally. An
increasing number of Salmonella infections are resistant to antibiotics, and many of the …

Many bacteria can exchange genetic material through horizontal gene transfer (HGT)
mediated by plasmids and plasmid-borne transposable elements. Here, we study the …

Non-typhoidal Salmonella enterica is a common cause of diarrhoeal disease; in humans,
consumption of contaminated poultry meat is believed to be a major source. Brazil is the …

Plasmids are genetic elements that enable rapid adaptation and evolution by transferring
genes conferring selective advantages to their hosts. Conjugative plasmids are …

The large, broad host range IncC plasmids are important contributors to the spread of key
antibiotic resistance genes and over 200 complete sequences of IncC plasmids have been …

Bacteria have evolved defence mechanisms against bacteriophages. Restriction-
modification systems provide innate immunity by degrading invading DNAs that lack proper …