Comparative oncology is a field of study that has been recently adopted for studying cancer
and developing cancer therapies. Companion animals such as dogs can be used to …

Simple Summary Genetic molecular testing is starting to become part of standard clinical
practice for dogs with cancer as it can assist veterinarians with diagnosis, provide …

Prostate cancer (PCa) in dogs is a highly malignant disease akin to its human counterpart. In
contrast to the situation in humans, multi-gene approaches facilitating risk stratification of …

Prostate cancer (PCa) is one of the most common malignancies for males, but very little is
known about its pathogenesis. This study aimed to identify novel biomarkers associated with …

Simple Summary Bone metastasis can develop from several tumor subtypes, and the
presence of bone metastasis confers a negative prognosis to patients. In dogs, a small …

The aberrant activation of HER2 has a pivotal role in bone metastasis implantation and
progression in several tumor types, including prostate cancer (PC). Trastuzumab and other …

Past studies have confirmed that aberrant activation of the Wnt/β-catenin signaling is
associated with tumorigenesis and metastasis in breast cancer, while the role of platelet …

Simple Summary Prostate cancer (PC) is one of the main types of cancer that affects the
male population worldwide. In recent decades, there has been a significant evolution in the …

Background Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC)
are typically characterized by metastasis and chemoresistance. Cell lines are important …

Dogs are one of few species that naturally develop prostate cancer (PCa), which clinically
resembles aggressive, advanced PCa in humans. Moreover, PCa-tumor samples from dogs …