Voltage‐gated calcium channels are essential players in many physiological processes in
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …

This review summarises genetic studies in which calcium channel genes have been
connected to the spectrum of neuropsychiatric syndromes, from bipolar disorder and …

Highly efficient phage-based Escherichia coli homologous recombination systems have
recently been developed that enable genomic DNA in bacterial artificial chromosomes to be …

L-type calcium channels regulate a diverse array of cellular functions within excitable cells.
Of the four molecularly defined subclasses of L-type Ca channels, two are expressed …

L-type calcium channels couple membrane depolarization in neurons to numerous
processes including gene expression, synaptic efficacy, and cell survival. To establish the …

Nociceptive sensory neurons are unusual in expressing voltage-gated inward currents
carried by sodium channels resistant to block by tetrodotoxin (TTX) as well as currents …

This review addresses the localized regulation of voltage-gated ion channels by
phosphorylation. Comprehensive data on channel regulation by associated protein kinases …

Voltage-gated L-type Ca2+ channels are key determinants of synaptic integration and
plasticity, dendritic electrogenesis, and activity-dependent gene expression in neurons …

Concerted activation of different voltage-gated Ca 2+ channel isoforms may determine the
kinetics of insulin release from pancreatic islets. Here we have elucidated the role of R-type …

To develop our understanding of myosin-1a function in vivo, we have created a mouse line
null for the myosin-1a gene. Myosin-1a knockout mice demonstrate no overt phenotypes at …