Synthetic chlorins, possible surrogates for chlorophylls, prepared by derivatization of porphyrins

M Taniguchi, JS Lindsey - Chemical reviews, 2017 - ACS Publications
Chlorophylls make Earth green, are the central constituents in the engine of photosynthesis,
and not surprisingly have garnered immense attention. A chlorin, the core chromophore of a …

Conjugated photosensitizers for imaging and PDT in cancer research

JCS Simões, S Sarpaki… - Journal of medicinal …, 2020 - ACS Publications
Early cancer detection and perfect understanding of the disease are imperative toward
efficient treatments. It is straightforward that, for choosing a specific cancer treatment …

Novel Foscan®-derived ring-fused chlorins for photodynamic therapy of cancer

AI Mata, NAM Pereira, AL Cardoso… - Bioorganic & Medicinal …, 2023 - Elsevier
Photodynamic therapy (PDT) is an established anticancer treatment that combines the use
of a photosensitiser (PS) and a light source of a specific wavelength for the generation of …

[PDF][PDF] Syntheses of bacteriochlorins and isobacteriochlorins

C Brückner, L Samankumara… - Handbook of porphyrin …, 2012 - academia.edu
Porphyrins are fully unsaturated tetrapyrrolic macrocycles linked by methylene carbons. The
chemical and physical properties of porphyrins are mainly determined by the presence of a …

Platinum (II) ring-fused chlorins as near-infrared emitting oxygen sensors and photodynamic agents

NAM Pereira, M Laranjo, J Casalta-Lopes… - ACS medicinal …, 2017 - ACS Publications
Novel near-infrared luminescent compounds based on platinum (II) 4, 5, 6, 7-
tetrahydropyrazolo [1, 5-a] pyridine-fused chlorins are described. These compounds have …

meso-Tetrakis(pentafluorophenyl)porphyrin-Derived Chromene-Annulated Chlorins

MA Hyland, MD Morton… - The Journal of Organic …, 2012 - ACS Publications
The synthesis of mono-and bis-chromene-annulated meso-(pentafluorophenyl) chlorins
from meso-tetrakis (pentafluorophenyl) porphyrins by an OsO4-mediated dihydroxylation …

Platinum (II) ring-fused chlorins as efficient theranostic agents: Dyes for tumor-imaging and photodynamic therapy of cancer

M Laranjo, MC Aguiar, NAM Pereira, G Brites… - European Journal of …, 2020 - Elsevier
The discovery of Pt-chlorin-type theranostic agents is described. Luminescent Pt (II) 4, 5, 6, 7-
tetrahydropyrazolo [1, 5-a] pyridine-fused chlorins, with different degrees of hydrophilicity …

Advances on photodynamic therapy of melanoma through novel ring-fused 5, 15-diphenylchlorins

NAM Pereira, M Laranjo, J Pina, ASR Oliveira… - European Journal of …, 2018 - Elsevier
The synthesis, photophysical behaviour and photosensitization ability of novel 4, 5, 6, 7-
tetrahydropyrazolo [1, 5-a] pyridine-fused 5, 15-diphenylchlorins against melanoma cells are …

Merging pyridine (s) with porphyrins and analogues: An overview of synthetic approaches

MCS Vallejo, MJA Reis, AMVM Pereira, VV Serra… - Dyes and …, 2021 - Elsevier
Synthetic methodologies leading to porphyrinoids conjugated to pyridyl/pyridinium units are
of longstanding interest in view of the possible application of the obtained derivatives in …

Photophysics of Glycosylated Ring‐Fused Chlorin Complexes and Their Photosensitizing Effects on Cancer Cells

IU Hageberg, K Arja, BE Vindstad, JK Bergvoll… - …, 2023 - Wiley Online Library
The future of photodynamic therapy (PDT) as a promising cancer treatment relies on the
development of new selective and effective photosensitizers (PS) with improved …